- ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study to investigate the safety, tolerability, pharmacokinetics, and early signs of biological activity of danegaptide following oral administration in participants with diabetic macular edema
This study is testing a new medicine, danegaptide, for people with diabetic macular edema. Researchers want to see if it's safe, how the body handles it, and if it shows early signs of working to improve this eye condition.
Germany - active not recruiting
A Real-World Study to Gain Clinical Insights Into Roche Ophthalmology Products
This study looks at how well certain eye medicines from Roche work for conditions like wet macular degeneration and diabetic eye disease in real patients. It's about understanding long-term results and why doctors choose specific treatments, without changing how patients are usually cared for.
United States · Argentina · Australia - active not recruiting
Observational Study of Adult Participants With Diabetic Macular Edema and Suboptimal Response to Anti-Vascular Endothelial Growth Factor Treated With Dexamethasone Intravitreal Implant
This study looks at how a medicine called a dexamethasone implant works for adults with blurry vision from diabetes (Diabetic Macular Edema) whose previous treatment didn't work well enough. It's an observational study, meaning researchers will just watch how patients do with the implant as part of their regular care. About 327 people globally will take part.
Belgium · China · Germany - recruitingPHASE3
CAPRI: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME
This study is testing a new eye treatment, EYP-1901, against an existing one, Aflibercept, for people with diabetic macular edema (DME). It aims to see if the new treatment works just as well to improve or keep vision stable.
United States · Brazil · Czechia - active not recruitingPHASE4
Treat & Extend Versus Fixed Dosing With Faricimab for Management of Diabetic Macular Edema: A Pragmatic, Multi-center, Open-label, Randomized, Controlled Trial
This study is looking at new ways to treat diabetic macular edema, an eye condition caused by diabetes. It compares two different schedules for giving a new medicine called faricimab to see which works best for patients in their daily lives.
United States · Australia · Canada