Diabetic Macular Edema (DME) research hub
6 indexed studies · 5 currently recruiting
- recruitingTherapeutic confirmatory (Phase III)
A Phase 3 Double-masked, Randomized, Multicenter Study of the Efficacy and Safety of OCS-01 Eye Drops in Subjects With Diabetic Macular Edema
This study is looking at new eye drops for a condition called diabetic macular oedema (DMO). Researchers want to see if the drops can improve eyesight and if they are safe to use. It's for adults aged 18 and over.
Italy · France · Germany - recruitingPhase II and Phase III (Integrated)
A Phase 2/3 Double-masked, Randomized, 2-stage, Multicenter Study of the Efficacy and Safety of OCS-01 Eye Drops in Subjects With Diabetic Macular Edema
This study looks at eye drops for diabetic macular edema (DME), a common eye problem caused by diabetes. Researchers want to see if the eye drops can help improve vision and reduce swelling in the back of the eye.
Spain · Hungary - recruitingTherapeutic exploratory (Phase II)
A Multi-Center, Randomized, Parallel-Group, Phase 2, Masked, Three-Arm Trial to Compare Safety, Tolerability, Efficacy, and Durability of Two Dose Levels of Suprachoroidal Sustained-Release OXU-001 (Dexamethasone Microspheres; DEXAspheres®) Using the Oxulumis® Illuminated Microcatheterization Device Compared with Intravitreal Dexamethasone Implant (OZURDEX®) in Subjects with Diabetic Macular Edema (OXEYE).
This study looks at a new treatment called OXU-001 for diabetic macular edema (DME), a common eye condition. It compares OXU-001 with an existing treatment, OZURDEX, to see which is safer and works better at improving eyesight and reducing swelling in the eye.
Hungary · Spain - active not recruitingPHASE2, PHASE3
A Study to Evaluate the Efficacy and Safety of 2 Doses of Remigromig (EYE103) Compared With Ranibizumab (0.5 mg) in Participants With DME
This study is looking at a new medicine, EYE103, for people with a common eye condition called diabetic macular oedema (DME). It compares EYE103 with a standard treatment, ranibizumab, to see if it's safe and helps improve vision.
United States · Argentina · Australia - recruiting
Investigating the Metabolic and Lipidomic Profiles That Are Associated With Varying Grades of Diabetic Maculopathy and Retinopathy in South Wales
This study in South Wales looks at how diabetes affects your eyes. We're checking blood and urine to understand why some people get worse eye damage. We also check gut bacteria. Our aim is to find new ways to protect your sight.
United Kingdom - recruitingPHASE3
CAPRI: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME
This study is testing a new eye treatment, EYP-1901, against an existing one, Aflibercept, for people with diabetic macular edema (DME). It aims to see if the new treatment works just as well to improve or keep vision stable.
United States · Brazil · Czechia