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Disorders characterized by a deficit in GABAergic signaling and cerebellar circuitry. research hub

2 indexed studies · 0 currently recruiting

ongoing, recruitingHuman Pharmacology (Phase I)- Other
PainCart Study Evaluating the Analgesic Profile of SAGE-319
This study is looking into a new medicine, SAGE-319, to see how it helps with pain. It's for people with certain health conditions where brain signals causing pain might not be working quite right. Researchers want to understand how this medicine works and if it can reduce pain.
Netherlands
ongoing, recruitingHuman Pharmacology (Phase I)- Other
A Randomized, Double-Blind (Sponsor-Unblinded), Placebo-Controlled, Single And Multiple Ascending Dose Study To Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Bioavailability and Food Effect (Open-Label) of Sage-319 in Healthy Adult Participants.
This study is looking at a new medicine called Sage-319 in healthy adults. It aims to check if the medicine is safe, how the body handles it, and if it works as expected. We'll also see how food affects it. This is an early stage of testing.
Netherlands