Early Alzheimer’s Disease research hub
6 indexed studies · 3 currently recruiting
- authorisedTherapeutic exploratory (Phase II)
An Exploratory Phase 2 Multicenter, Double-blind, Randomized, Placebo controlled, Parallel Group Study to Investigate the Safety, Tolerability, and Efficacy of TML-6 in Early Alzheimer’s Disease
This clinical trial tests a new potential medicine called TML-6 for people living with early Alzheimer’s disease. Researchers want to see if it is safe and whether it can help slow down memory loss over one year. Participants will receive either the study medicine or an inactive dummy pill (placebo).
Sweden - recruitingHuman Pharmacology (Phase I)- Other
Characterization of Immune Response in Participants from a Posdinemab Study
This study is looking at how a trial medicine called Posdinemab affects the body's defence system in people with early Alzheimer's disease. Researchers want to understand if and how this medicine changes the immune system. Anyone aged 18 or over, male or female, with early Alzheimer's might be able to take part.
Netherlands · Spain · France - recruitingPHASE2
A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)
This study is looking into a new medication called MK-2214 for people with early Alzheimer's disease. Researchers want to see if it can slow down changes in the brain that cause memory and thinking problems. They will also check if it's safe for people to take.
United States · Argentina · Australia - recruitingTherapeutic exploratory (Phase II)
A Randomized, Double-blind, Placebo-controlled, Parallel-group, Multicenter Study with a Long-Term Extension Treatment Period to Assess the Efficacy and Safety of JNJ-63733657, an Anti-tau Monoclonal Antibody, in Participants with Early Alzheimer's Disease
This study is testing a new medicine, JNJ-63733657, for people with early Alzheimer's disease. Researchers want to see if it's safe and helps improve memory and thinking over two years, compared to a dummy drug.
Sweden · France · Belgium - active not recruitingPHASE3
A Study to Confirm Safety and Efficacy of Lecanemab in Participants With Early Alzheimer's Disease
This study is testing a new medicine, lecanemab, for people in the early stages of Alzheimer's disease. Researchers want to see if it's safe and helps slow down memory and thinking problems. Some people will get the medicine, and others a dummy treatment.
United States · Australia · Canada - active not recruitingPHASE3
Long-term Extension of Phase 3 Study of ALZ- 801 in APOE4/4 Early AD Subjects
This study looks at the long-term safety and effects of a drug called ALZ-801 for people with early Alzheimer's disease who have a specific genetic make-up (APOE4/4). It's an ongoing study where all participants receive the active drug. The aim is to see how well it works and if it's safe over a longer period.
United States · Canada · United Kingdom