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ESKD participants with history of secondary hyperparathyroidism (SHPT) undergoing maintenance hemodialysis research hub

2 indexed studies · 0 currently recruiting

ongoing, recruitingTherapeutic confirmatory (Phase III)
A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Efficacy and Safety of Dose-Titrated PLS240 in the Treatment of Secondary Hyperparathyroidism in Individuals with End Stage Kidney Disease on Hemodialysis (PATH-2) With an Open-Label Extension
This study is testing a new medicine, PLS240, for people with serious kidney disease on dialysis. It aims to see if PLS240 can help control a hormone called PTH and if it's safe to use. Patients will either get PLS240 or a dummy pill.
Portugal · Bulgaria · Spain
ongoing, recruitingTherapeutic confirmatory (Phase III)
A PHASE 3 RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY EVALUATING THE EFFICACY AND SAFETY OF DOSE-TITRATED PLS240 IN THE TREATMENT OF SECONDARY HYPERPARATHYROIDISM IN INDIVIDUALS WITH END STAGE KIDNEY DISEASE ON HEMODIALYSIS (PATH-1) WITH AN OPEN-LABEL EXTENSION
This study is looking into a new medication called PLS240 for people with advanced kidney disease on dialysis. It aims to see if PLS240 can help manage a common kidney-related hormone problem called secondary hyperparathyroidism, and to check if it's safe to use.
Poland · Portugal · Spain