Fibrodysplasia Ossificans Progressiva research hub
4 indexed studies · 2 currently recruiting
- recruitingTherapeutic confirmatory (Phase III)
Phase 3 Randomized, Placebo-Controlled Study to Assess Safety, Tolerability and Efficacy of Garetosmab in Patients with Fibrodysplasia Ossificans Progressiva
This Phase 3 clinical trial is testing a new medicine called garetosmab for adults with fibrodysplasia ossificans progressiva (FOP). Researchers want to see if garetosmab can safely stop or slow down abnormal bone growth in muscles and joints, reduce painful flare-ups, and help protect movement and daily function.
Finland · Italy · Spain - recruitingTherapeutic exploratory (Phase II)
A Phase 2 study to assess the efficacy and safety of 2 dosage regimens of oral fidrisertib (IPN60130) for the treatment of fibrodysplasia ossificans progressiva in male and female paediatric and adult participants.
This study is testing a new medicine, fidrisertib, for children and adults with Fibrodysplasia Ossificans Progressiva (FOP). We want to see if it can slow down the new bone growth and reduce flare-ups, and if it's safe to use. Some participants will receive a dummy pill (placebo).
Sweden · Germany · France - active not recruitingPHASE3
A Study to Assess Safety, Tolerability and Efficacy of Garetosmab Versus Placebo Administered Intravenously (IV) in Adult Participants With Fibrodysplasia Ossificans Progressiva (FOP)
This study is looking into a new drug, garetosmab, for adults with Fibrodysplasia Ossificans Progressiva (FOP). We want to find out if it's safe, how well it works, and if it helps with FOP symptoms. It's a Phase 3 trial, meaning it's in the later stages of testing.
United States · Australia · Brazil - active not recruitingPHASE2
Saracatinib Trial TO Prevent FOP
This study is testing a new drug called Saracatinib (also known as AZD0530) for people with Fibrodysplasia Ossificans Progressiva (FOP). It aims to see if the drug can prevent new bone from growing in soft tissues, which is a key problem in FOP.
Germany · Netherlands · United Kingdom