Gastric cancer, Gastric Adenocarcinoma, GastroEsophageal Cancer research hub

A Phase 2, Multicenter, Open-Label Study of DKN-01 in Combination with Tislelizumab ± Chemotherapy as First-Line or Second-Line Therapy in Adult Patients with Inoperable, Locally Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma (DisTinGuish)

This study is testing new combinations of medicines for advanced stomach or gastroesophageal junction cancer. It's looking at how safe they are and how well they help control the cancer, especially in people with a specific marker called DKK1-high.