Gastrointestinal Neoplasms research hub
7 indexed studies · 5 currently recruiting
- recruiting
Evaluation of Neoplasia With Artificial Intelligence in Gastrointestinal Endoscopy
Doctors are testing new computer programs, called AI, to help find early signs of cancer in the stomach and bowel during endoscopy procedures. This study uses existing endoscopy images and videos to see how well AI can spot these changes.
United Kingdom - active not recruitingPHASE1
First-in-human Study of IDRX-42 in Participants With Metastatic and/or Unresectable Gastrointestinal Stromal Tumors
This study is testing a new drug, IDRX-42, for people with advanced gastrointestinal stromal tumors (GIST). It's the first time this drug is being used in humans. We want to see if it's safe, how the body handles it, and if it helps shrink tumors.
United States · Belgium · China - recruitingNA
Interaction Between Host, Microenvironment and Immunity on Gastrointestinal Neoplasms
This study looks at how your body, its tiny environment, and your immune system affect digestive cancers like bowel or pancreatic cancer. Researchers want to understand these connections to improve treatments and predict patient outcomes.
France - active not recruitingPHASE3
Assessing Durvalumab and FLOT Chemotherapy in Resectable Gastric and Gastroesophageal Junction Cancer
This study looks at a new drug, durvalumab, and standard chemotherapy (FLOT) for stomach or food pipe cancer that can be removed by surgery. It aims to see if this combination, given before and after the operation, is safe and effective.
United States · Argentina · Belgium - recruitingPHASE1, PHASE2
A Study to Test the Safety and Effectiveness of GSK5764227, Alone or With Other Treatments, in Participants With Advanced Gastrointestinal Cancers That Cannot be Surgically Removed
This study is testing a new medicine, GSK5764227, for advanced bowel or pancreatic cancer that can't be removed by surgery. It will check how safe and effective it is, and how the body handles it in people who have already had other treatments.
United States · Australia · Belgium - recruitingPHASE3
A Study of IDRX-42 (GSK6042981) Versus (vs) Sunitinib in Participants With Gastrointestinal Stromal Tumors After Imatinib Therapy
This study is testing a new drug, IDRX-42, for a type of cancer called GIST. It's for adults whose GIST has spread or can't be removed with surgery, and who have already tried another drug called imatinib. Researchers want to see if IDRX-42 works better and is safer than sunitinib.
United States · Australia · Belgium - recruitingPHASE3
Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
This study is testing a new medicine, PF-08634404, alongside standard chemotherapy for adults with colorectal cancer that has spread. We want to see if this new combination helps more than an existing treatment with chemotherapy for people whose cancer has returned or spread.
United States · Argentina · Australia