Childhood Extracranial Germ Cell Tumor research hub
8 indexed studies · 5 currently recruiting
- recruitingPHASE3
Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors
This study looks at how best to treat a type of cancer called germ cell tumours in children and adults. It compares simply watching the tumour after surgery with different chemotherapy treatments to see which works best and causes fewer side effects.
United States · Australia · Canada - active not recruiting
A Study of miRNA 371 in Patients With Germ Cell Tumors
This study looks at a special marker called miRNA 371 in blood tests for people with germ cell tumours. The aim is to see if this marker can help predict if the cancer might return, allowing doctors to better understand and manage the risk.
United States · Canada · Guam - active not recruitingNA
Living After a Rare Cancer of the Ovary: Chronic Fatigue, Quality of Life and Late Effects of Chemotherapy
This study looks at how women who have had rare ovarian cancer and chemotherapy are living years later. It checks things like tiredness and general well-being to understand the long-term effects of their treatment and condition.
France - recruitingPHASE3
Thromboprophylaxis in Good and Intermediate Prognosis Advanced Germ Cell Tumors
This study aims to see if a blood clot prevention medicine, called thromboprophylaxis, can reduce dangerous blood clots in men with advanced germ cell cancer who are having chemotherapy. We want to find out if it's safe and effective.
France - recruitingPHASE1
Phase 1, Safety and Tolerability Study of XmAb541 in Advanced Solid Tumors
This study is testing a new medicine called XmAb541 for people with certain advanced cancers that haven't responded to other treatments. Doctors want to see if it's safe, what dose works best, and if it can help shrink or control the cancer. It's a very early-stage trial.
United States · Belgium · Denmark - active not recruitingPHASE3
Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients With Relapsed or Refractory Germ Cell Tumors
This study compares two chemotherapy treatments for germ cell tumours that have returned or didn't respond to previous treatment. It looks at a standard chemotherapy plan versus a stronger plan with a stem cell transplant to see which works better.
United States · Australia · Belgium - recruiting
Observational Study for Assessing Treatment and Outcome of Patients With Primary Brain Tumours Using cIMPACT-NOW and 2021 WHO Classification
This study looks at how new ways of classifying brain tumours (cIMPACT-NOW and 2021 WHO) help us understand treatment and what to expect. Researchers want to see if these new classifications group patients better and lead to clearer treatment guidelines for different types of brain tumours.
Austria · Belgium · France - recruitingPHASE3
Accelerated v's Standard BEP Chemotherapy for Patients With Intermediate and Poor-risk Metastatic Germ Cell Tumours
This study looks at a new way to give chemotherapy for a type of cancer called germ cell tumour. We're comparing a faster treatment schedule (accelerated BEP) with the usual one, to see if it works better for people with more serious forms of the disease.
United States · Australia · New Zealand