- authorisedTherapeutic exploratory (Phase II)
A Placebo-Controlled, Multicenter, Randomized Phase 2 Trial Evaluating the Efficacy and Safety of Felzartamab Compared to Placebo in Adult Participants with Graves’ Disease
This study tests a new medicine called felzartamab in adults with Graves’ disease. Researchers want to find out if felzartamab can help restore normal thyroid hormone levels safely, allowing people to reduce or completely stop taking their regular anti-thyroid tablets after 24 weeks.
Italy · Spain - recruitingNA
Prospective Evaluation of OptiThyDose
This study is testing a new tool called OptiThyDose. It's designed to help doctors give the right amount of medicine to children with certain thyroid conditions, like Congenital Hypothyroidism and Graves' Disease, to improve their health and avoid side effects.
France · Switzerland - recruitingPHASE2
A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease
This study is looking for adults with Graves' disease whose thyroid is overactive despite medication. It aims to see if a new medicine, IMVT-1402, is safe and helps control their thyroid better than a dummy medicine. We want to find a better treatment.
United States · Australia · Brazil - recruitingNA
Thyroid Artery Goitre Embolization Trial A Pilot Study Investigating Thyroid Artery Embolisation as a Treatment for Large Thyroid Nodules
This study looks at a new treatment called Thyroid Artery Embolization (TAE) for large, non-cancerous lumps in the throat (thyroid nodules) or overactive thyroids. It's a small study in the UK to see if TAE is safe and to gather शुरुआती information.
United Kingdom - recruitingPHASE2
A Study to Investigate the Efficacy and Safety of Rilzabrutinib in Adult Participants With Graves' Disease
This study is testing a new medicine, rilzabrutinib, for adults with an overactive thyroid caused by Graves' disease, including those with eye problems. We want to see how well it works and if it's safe at two different doses.
Argentina · Canada · Chile - authorisedHuman Pharmacology (Phase I)- First administration to humans
A study to test single and multiple doses of MER511 given to adults with Graves’ disease
This study is looking into a new medicine, MER511, for people with an overactive thyroid caused by Graves' disease. It will test how safe the medicine is and how it works in the body when given in different doses, for the very first time in people.
Spain - recruitingPHASE2
A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease
This study is testing a new medicine, IMVT-1402, for adults with Graves' disease whose thyroid is still overactive despite current treatment. We want to see if it works, is safe, and is well-tolerated. It's a Phase 2 trial. You can find out more if you're interested.
United States · Belgium · Georgia - enrolling by invitationPHASE2
A Long-Term Extension Study of IMVT-1402 in Adult Participants With Graves' Disease (GD)
This study is for adults with Graves' Disease who have already taken part in another trial for a medicine called IMVT-1402. It's a long-term study to see how well this medicine works and if it's safe over a longer period, helping us understand more about this treatment.
United States · Australia · Bulgaria