Heart Failure With Preserved Ejection Fraction (HFPEF) research hub
11 indexed studies · 9 currently recruiting
- recruitingPHASE2
Coronary Artery Stents in Heart Failure With Preserved Ejection Fraction
This study looks at whether fitting tiny tubes called stents into narrowed heart arteries can improve the quality of life for people with a common heart problem called HFpEF. Researchers want to see if this procedure helps them feel better.
United Kingdom - recruiting
Characteristics, Phenotypes, and TRAITS of Heart Failure With Preserved Ejection Fraction (TRAITS-HFpEF)
This study, called TRAITS-HFpEF, wants to understand a type of heart failure called HFpEF. We don't fully know why people get it or how best to treat it. By collecting information from patients, researchers hope to find new ways to diagnose and treat this condition, and learn more about how it affects people's lives.
United Kingdom - not yet recruitingPHASE3
A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
This study is looking at a new medicine called Elecoglipron for people with certain types of heart failure. It compares Elecoglipron to a dummy medicine (placebo) to see if it helps improve heart health outcomes for adults already taking other heart failure medications, including dapagliflozin.
United States · Argentina · Australia - recruiting
The Use of Advanced Imaging in HFpEF
This study investigates new ways to diagnose a type of heart failure called HFpEF, where the heart is stiff. We're using advanced scans to help identify this condition more accurately, aiming to get people the right treatment sooner and improve their symptoms and quality of life.
United Kingdom - recruiting
Determination of the Prevalence of Unrecognized Heart Failure Among Patients at Risk in Urban Areas Across Germany Using CMR
This study in Germany is looking for people aged 40-69 who are at risk of heart failure but don't have symptoms. It uses mobile MRI scans and other tests to find a better way to spot this condition early and offer help in big cities.
Germany - recruitingNA
Treating Atrial Fibrillation in Heart Failure With Preserved Ejection Fraction: Ablation or Medication
This study looks at two ways to treat an irregular heartbeat (atrial fibrillation) in people with certain types of heart failure: a procedure called ablation or daily medicines. It aims to see which treatment works better for improving quality of life, reducing hospital stays, and helping people live longer.
Canada - ongoing, recruitingTherapeutic exploratory (Phase II)
A Phase 2A, Double-blind, Randomized, Placebo-controlled, Multi-center Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BMS-986435/MYK-224 in Participants with Heart Failure with Preserved Ejection Fraction (HFpEF)
This study is looking into a new medication called BMS-986435/MYK-224 for people with a type of heart failure called HFpEF. It's in the early stages and aims to check if the medicine is safe and how the body handles it, compared to a dummy medicine.
Spain · Poland · Italy - recruiting
UK Heart Failure With Preserved Ejection Fraction
This study looks into a type of heart failure called HFpEF, where the heart still pumps well but has trouble relaxing. It aims to understand why it happens, find better ways to diagnose it, and discover new treatments to help people feel better.
United Kingdom - recruitingNA
ELEVATE-HFpEF Clinical Study
This study looks at whether a special type of pacemaker can help people with a common heart condition called heart failure with preserved ejection fraction (HFpEF). It aims to see if personalising the pacemaker's settings improves symptoms and quality of life.
United States · Australia · Austria - ongoing, recruitingHuman Pharmacology (Phase I)- First administration to humans
A Study to Learn About the Study Medicine Called PF-07293893 in Healthy Adults, and How Different Doses of Study Medicine are Tolerated and Act in the Body.
This study is testing a new medicine called PF-07293893 in healthy adults. It aims to understand how different amounts of the medicine are handled by the body and if they are safe. It’s the first time this medicine will be given to people.
Belgium - recruiting
The Role of Epicardial Adiposity in Heart Failure With Preserved Ejection Fraction
This study looks at how having extra fat around the heart affects people with a type of heart failure called HFpEF. Researchers are using scans and tests to see if this fat makes the heart work less well, hoping to find new ways to treat the condition.
United Kingdom