Idiopathic inflammatory myopathy research hub
5 indexed studies · 4 currently recruiting
- recruitingTherapeutic exploratory (Phase II)
Intravenous immunoglobulin and prednisone vs. prednisone in newly diagnosed myositis: a double blind randomized clinical trial
This study looks at a new treatment approach for people recently diagnosed with myositis, an illness causing muscle weakness and swelling. Researchers are testing whether adding an antibody drip (immunoglobulin) to standard steroid tablets helps patients recover muscle strength and feel better faster than steroid tablets alone.
Netherlands - recruitingPHASE2, PHASE3
RESET-Myositis: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Idiopathic Inflammatory Myopathy or Juvenile Idiopathic Inflammatory Myopathy
This study looks at a new treatment called CABA-201 for conditions that cause muscle weakness and inflammation, like dermatomyositis. It aims to see how safe and effective this treatment is for adults and children whose condition hasn't improved with usual care.
United States · Germany · Italy - recruitingPHASE1
A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease
This study looks at a new treatment called ALLO-329 for serious autoimmune diseases like lupus and scleroderma. It's the first time this treatment is being used in people. Doctors want to see if it's safe, how well people tolerate it, and if it shows early signs of helping patients get better.
United States · Canada - recruitingPHASE1
A Study of CC-97540, CD-19-Targeted Nex-T CAR T Cells, in Participants With Severe, Refractory Autoimmune Diseases (Breakfree-1)
This study is testing a new cell therapy called CC-97540 for severe autoimmune diseases like lupus and rheumatoid arthritis. It aims to see if it's safe, how well it works, and how the body handles it, especially when other treatments haven't helped.
United States · Belgium · France - active not recruiting
MYOPROSP - a Prospective Cohort Study in Myositis
This study, MYOPROSP, aims to better understand myositis, a group of rare muscle diseases. We're looking at adults with suspected or confirmed myositis to collect information and samples. This helps us learn more about diagnosing the condition, how it progresses, and how new treatments work.
United Kingdom