Immunoglobulin A Nephropathy (IgAN) research hub
5 indexed studies · 4 currently recruiting
- recruitingTherapeutic confirmatory (Phase III)
A Randomized, Multicenter, Double-blind, Parallel-group, Active-control Study of the Efficacy and Safety of Sparsentan for the Treatment of Immunoglobulin A Nephropathy (PROTECT)
This phase 3 clinical study tests a new medicine called sparsentan for adults with IgA nephropathy, a serious kidney condition. Researchers want to see if sparsentan is better at reducing protein leaks in urine and protecting kidney function over time compared to a standard medicine called irbesartan.
Poland · Portugal · Belgium - authorisedTherapeutic exploratory (Phase II)
A Phase 2, Multicenter, Randomized, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Tolerability of ARGX-121 SC in Adult Participants With Primary IgA Nephropathy
This phase 2 clinical trial is testing a new injection called ARGX-121 for adults with IgA nephropathy, a kidney condition. Researchers want to see if the medicine is safe and if it can reduce the amount of protein leaking into the urine, which helps protect kidney health over time.
Spain · Poland · Czechia - recruitingTherapeutic exploratory (Phase II)
A Phase 2, Randomized, Double‑blind, Placebo‑controlled, Dose‑finding Study to Evaluate the Efficacy and Safety of ALXN2050 in Adult Participants with Proliferative Lupus Nephritis (LN) or Immunoglobulin A Nephropathy (IgAN)
This study is testing a new medicine, ALXN2050, for adults with kidney diseases called lupus nephritis or IgA nephropathy. Researchers want to see if the medicine can reduce protein in the urine and if it's safe.
Germany · Spain · Italy - recruitingTherapeutic exploratory (Phase II)
A Phase 2, Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Ravulizumab in Adult Participants With Proliferative Lupus Nephritis (LN) or Immunoglobulin A Nephropathy (IgAN)
This study is testing a new medicine, Ultomiris, for adults with kidney diseases called Lupus Nephritis or IgA Nephropathy. Doctors want to see if it reduces protein in their urine and helps their kidneys work better, compared to a dummy medicine.
Italy · Poland · Spain - recruitingPHASE3
A Study to Learn About the Effects of Felzartamab Infusions on Adults With Immunoglobulin A Nephropathy (IgAN)
This study looks at a new medicine called felzartamab for adults with a kidney disease called IgA nephropathy (IgAN). Researchers want to see if it reduces protein in the urine and helps kidney function. It involves infusions and careful monitoring.
United States · Argentina · Australia