- ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
A single-dose, open-label, randomized, two-period, two-sequence, crossover pivotal bioequivalence study on 400 mg / 5 mL amoxicillin + 57 mg / 5 mL of clavulanic acid powder for oral suspension in healthy volunteers under fed conditions.
This study compares a new liquid antibiotic medicine for infections with an existing one. We want to see if they work the same way in healthy adults after eating. It's a key step to make sure new medicines are just as good as older ones.
Czechia - active not recruitingNA
Barrier-Protect Study
This study looks at a special plaster with iodine to see if it can stop infections after heart device operations. We want to know if putting it on early helps keep the surgery area clean.
Canada - recruitingNA
The Irrigation or No Irrigation in Simple Lacerations Trials
This study is looking into whether cleaning simple cuts with water (irrigation) actually helps prevent infection. We want to see if not cleaning them with water is just as safe, potentially saving time and money in emergency care.
Canada - recruiting
Metagenomics for Ocular Inflammation
This study uses a special test called 'metagenomic sequencing' to find hidden infections in people with eye inflammation. Current tests often miss these. By finding the infection, doctors hope to offer better, more targeted treatments and improve our understanding of this condition.
United Kingdom - recruiting
Validation of Drug Assays in Various Biological Matrices
This study checks if tests for different medicines in body fluids are accurate. We're looking at infection drugs, birth control, and erectile dysfunction medicines. This helps make sure patients get the right treatment based on reliable test results.
United Kingdom - active not recruiting
Metagenomic Next-Generation Sequencing for the Diagnosis of Fracture-related Infection
This study is looking at a new, advanced DNA test called metagenomic sequencing, using Nanopore technology, to help diagnose infections that happen after a bone fracture. It compares this new test with the usual methods to see if it's better at finding the germs causing the infection.
France - enrolling by invitation
Real-world Multicentre Study of AZtreonam-AVIbactam Treatment With Infections or Suspected Infections Caused by Multidrug-resistant Gram-negative Bacteria
This study looks at how a new antibiotic, Aztreonam-Avibactam, works in real life for serious infections caused by very resistant bacteria. Researchers are checking if it helps patients get better and if it's safe, by looking at past and current patient information.
France - active not recruiting
Overview of Botriomycoma in Children with a Central Line: Epidemiology, Risk Factors, Treatments
This study looks at skin growths called botriomycomas near central lines in children needing special nutrition at home. It aims to understand why these growths appear and how best to treat them, as they can sometimes lead to infections and other problems.
France