- recruitingHuman Pharmacology (Phase I)- First administration to humans
A Randomised, Placebo-Controlled, Double-blind, Single and Multiple Ascending Dose, Phase 1 Study to Evaluate the Safety, Tolerability, and Pharmacokinetics Following Intravenous Administration of IRX-010 in Healthy Participants
This study is looking at a new medicine called IRX-010 for inflammatory diseases. It's the first time it’s being given to people, to check if it's safe and how the body handles it. They are looking for healthy adults to take part.
Netherlands - recruitingNA
68Gallium-FAPI46 PET/CT Imaging in Chronic Inflammatory and Fibrotic Diseases
This study looks at a new imaging test, called 68Ga-FAPI PET/CT, for people with long-term inflammatory and scarring conditions like arthritis or liver scarring. It aims to see if this new scan can help doctors diagnose these conditions better and track them over time.
France - recruiting
Evaluation of High Dose Prednisolone Pharmacokinetics in the Acute and Chronic Setting
This study looks at how your body handles prednisolone, a common anti-inflammatory medicine, especially at higher doses. We're trying to understand if prednisolone levels in your blood are consistent and if they change over time, which could help tailor treatment for conditions like asthma or thyroid eye disease.
United Kingdom - recruiting
Genetic Variants and Regulation of Specialized Pro-resolving Mediator
This study looks at how tiny changes in our genes might affect how our bodies handle inflammation. We're trying to understand why some people get long-term inflammatory diseases like arthritis and heart conditions, hoping to find new ways to treat them.
United Kingdom - recruiting
7 Tesla MRI Brain Imaging to Decipher Filgotinib's Mode of Analgesic Action in Rheumatoid Arthritis
This study uses special brain scans to understand how a new medicine, filgotinib, helps ease pain in people with rheumatoid arthritis. Researchers want to see if it works by affecting the brain's pain signals or by reducing swelling in the joints.
United Kingdom