- completed
Personalised treatment packages for adults with a learning disability
The PETAL study tests a personalised support programme for adults with learning disabilities who show aggressive behaviour. By tailoring care to each person's unique needs, researchers hope to help individuals and their carers better manage distress, improve everyday quality of life, and reduce the need for strong medications or hospital stays.
United Kingdom · England · Northern Ireland - recruiting
Early Positive Approaches to Support (E-PAtS) for families of young children with intellectual disability: a randomised controlled trial
This UK study tests 'E-PAtS', an 8-week group programme for parents and carers of young children with intellectual disabilities or developmental delays. It aims to see whether sharing practical tools and peer support improves family wellbeing, helps carers manage stress, and provides good value for public health services.
United Kingdom · England · Northern Ireland - recruitingPHASE4
Metformin for Antipsychotic-induced Weight Gain in Adults With Intellectual Disability
This study looks at whether a medicine called metformin can help adults with learning disabilities who've gained weight from antipsychotic medicines. These medicines are important, but weight gain can lead to other health problems.
Canada - not yet recruitingNA
A Cognitive Behavioral Therapy Approach to Addressing Anxiety in Children With ASD and Intellectual Disability
This study looks at a special type of talking therapy called 'Facing Your Fears' (FYF) for young people aged 12-18 with autism and intellectual disability who also experience anxiety. It aims to see how well this therapy works for them.
Canada - recruitingNA
Prospective Study to Assess Medical Performance of Optical Mapping and Long Read Sequencing in Detecting Numerical and Structural Chromosome Abnormalities
This study is looking at new genetic tests to better understand why some people experience infertility, learning difficulties, birth defects, or miscarriages. It compares these newer, more detailed tests to older ones, hoping to find better ways to spot problems with chromosomes.
France - recruiting
Neuropsychiatric Research Databases for People With Intellectual Disabilities and Epilepsy (REFINE)
This study aims to build a research database and register for people in the UK with intellectual disabilities and epilepsy. It will help researchers understand these conditions better and find people who might want to join future studies, with all personal details kept private where possible.
United Kingdom - recruiting
Impact of Sulphonylureas on Neurodevelopmental Outcomes in KCNJ11-related Intermediate Developmental Delay, Epilepsy and Neonatal Diabetes (iDEND) Syndrome
This study looks at how a diabetes medicine, sulphonylurea, affects brain development in children and adults with a specific genetic condition called iDEND syndrome. We want to see if starting this medicine early in life leads to better developmental outcomes.
United States · Italy · Norway - not yet recruiting
Search for Phenotype-modifying Genes in Patients With Intellectual Disabilities.
This study looks at DNA from people with learning disabilities to find genes that might change how the condition shows up. Researchers are re-examining existing genetic information to understand why some people are affected differently, hoping to improve understanding of these conditions.
France - recruiting
Evaluating the Treatment in the MZEB Aachen
This study looks at how people with learning disabilities and severe complex needs are cared for at a special German medical centre. Researchers want to understand who these patients are, what treatments they receive, and how their health progresses, to help improve care for others.
Germany