Improvement of cardiovascular outcomes in patients with advanced research hub
8 indexed studies · 5 currently recruiting
- recruitingTherapeutic confirmatory (Phase III)
TRACK - Treatment of cardiovascular disease with low dose Rivaroxaban in Advanced CKD.
The TRACK study tests whether a low-dose blood-thinning tablet called rivaroxaban can help protect people with advanced kidney disease from heart attacks, strokes, and circulation problems. Half of the participants take rivaroxaban, while the other half take a dummy tablet (placebo) to see if the medicine is safe and effective.
Germany · Belgium · France - recruitingNot Specified
LINK-UP: novel interventions in kidney disease - user perspectives
This study wants to learn how to better support people with kidney disease. Researchers will talk to patients, their families, and healthcare workers to understand what helps and what makes it harder to use tools like "My Kidneys & Me" to manage their health.
United Kingdom · England - active not recruiting
Meta-Analyses of the Effect of Plant Protein Versus Animal Protein on Cardiometabolic Risk
This study looks at lots of past research to see if swapping animal protein for plant protein makes a difference to health conditions like diabetes, heart problems, and kidney issues. They want to understand if eating more plant-based protein, like from beans or nuts, can be better for our health.
Canada - authorisedTherapeutic exploratory (Phase II)
A randomized controlled, two-arm (1:1 ratio) Phase IIa trial to assess the efficacy and safety of obinutuzumab in treating adults with de novo minimal change disease
This study is testing a new medicine called obinutuzumab for a kidney condition called minimal change disease. We want to see if it works as well as, or better than, current treatments, and if it's safe for adults.
Germany · Austria · France - active not recruitingPHASE1
A Study to Evaluate the Safety, Tolerability, and Effects on Blood and Urine Markers of Single Ascending Dose of GSK4771261 in Healthy Participants and Participants With Autosomal Dominant Polycystic Kidney Disease
This study is testing a new drug, GSK4771261, for kidney disease. It looks at how safe it is and what it does to the body in healthy people and those with a specific kidney condition called ADPKD.
United States · Belgium · Canada - not yet recruiting
Clinical Information System Impact on Hospitalized Patients With Chronic Disease
This study looks at how a new computer system in hospitals, called Connect Care, affects patients with ongoing health problems like diabetes or heart disease. Researchers are checking if the system helps reduce hospital readmissions or deaths within 30 days of leaving the hospital.
Canada - recruiting
A Study of Maribavir in Adults With Kidney Failure Who Have a Cytomegalovirus (CMV) Infection After Transplantation
This study looks at how safe a medicine called maribavir is for adults with serious kidney problems and a CMV germ infection after they've had an organ transplant. We're reviewing existing medical records to understand its effects without changing anyone's care.
Belgium · Estonia · France - recruitingPHASE3
A Study of Mezagitamab in Adults With Kidney Condition Called IgA Nephropathy
This study looks at a new medicine called mezagitamab for a kidney problem called IgA nephropathy. It compares mezagitamab to a dummy medicine to see if it lowers protein in the urine and helps protect kidneys. All adults over 18 with this condition can take part.
United States · Argentina · Australia