- active not recruiting
Genetic Determinants of Kidney Disease in People of African Ancestry With HIV
This study looks at why kidney problems are more common in people of African heritage living with HIV in the UK. It found that certain genes can increase this risk. The research aims to better understand these factors to improve care.
United Kingdom - active not recruitingNA
Clinical Impact of the IBox As an Early Intervention TooL
This study is looking at a new way to check on people who have had a kidney transplant. It’s called Predigraft. The aim is to see if using Predigraft can help doctors spot problems with the new kidney earlier, potentially leading to better long-term health for patients.
Austria · France · Germany - active not recruitingPHASE2
ETA and AT1 Antagonism in ANCA-vasculitis (SPARVASC)
This study looks at a new drug, sparsentan, for people with ANCA-associated vasculitis. It aims to see if blocking certain chemicals can help improve blood vessel health, which is important for preventing heart attacks and strokes in these patients.
United Kingdom - recruitingPHASE3
A Contrast Medium Sparing Strategy Using Automated CO2 Injection During PVI for Prevention of Major Adverse Kidney Events (MAKE)
This study looks at a new way to perform leg artery procedures for people with poor circulation. It aims to reduce kidney problems by using a special gas, carbon dioxide, instead of the usual X-ray dye, which can sometimes harm the kidneys.
Austria · Germany - active not recruitingPHASE3
Long Term Extension Study in Patients With Primary Hyperoxaluria
This study offers long-term treatment with DCR-PHXC for people, including children, with Primary Hyperoxaluria (PH). It checks if the treatment is safe and works well over time for this rare genetic kidney condition.
United States · Australia · Canada - recruitingPHASE2
A Study of the Safety and Activity of Sparsentan for the Treatment of Patients With Immunoglobulin A Nephropathy
This study looks at a new drug, Sparsentan, for people with kidney disease called IgA Nephropathy. It aims to see if the drug is safe and helpful in protecting the kidneys, both for newly diagnosed patients and those who have had a kidney transplant.
United Kingdom