- recruiting
Endovascular Preparation for Kidney Tranplantation
This study looks at a new way to prepare people for a kidney transplant when their blood vessels make a standard transplant difficult. It aims to see if a special tube (endoprosthesis) inserted into a blood vessel can help more people get a life-changing kidney.
France - recruiting
KTRSensor Scotland Study: An Observational Study Into Predictors and Diagnosis of Kidney Transplant Rejection
This study looks at people in Scotland who have had a kidney transplant. Researchers want to find early signs in urine that can predict if a new kidney might have problems, helping doctors improve care and outcomes for patients.
United Kingdom - recruiting
MEMRI and Kidney Disease
This study uses a special MRI scan to look at how kidney injury, kidney transplants, and other kidney problems affect your heart. Researchers want to find a new way to identify people at risk of heart problems and ongoing kidney disease, helping them get treatment earlier.
United Kingdom - not yet recruitingNA
Outcomes of a Pre-operative Exercise Programme for Live Donor and Recipient Kidney Transplant Patients
This study looks at whether exercising before a kidney transplant, using a smart device to track progress, can help live donors and people receiving kidneys. We want to see if this makes their recovery better after the operation.
United Kingdom - recruitingNA
Evaluation of Thiosulfate Enhanced Organ Preservation Solution in Kidney Transplantation
This study is testing a new way to keep donated kidneys healthy for transplant. We're using a special solution with sodium thiosulfate to protect kidneys from deceased donors, hoping to help them work better and last longer for people needing a new kidney.
Canada - recruiting
Multimorbidity and Cardiovascular Risk Factors After Renal Transplant
This study looks at the health of adults in the UK who have had a kidney transplant. Researchers want to understand how heart disease risks and other health issues change in the first year after their operation.
United Kingdom - ongoing, recruitingTherapeutic use (Phase IV)
The OPTIMIzE study;OPen label multicenter randomized Trial comparing standard IMmunosuppression with tacrolimus and mycophenolate mofetil with a low exposure tacrolimus regimen In combination with everolimus in de novo renal transplantation in Elderly patients.
This study looks at new ways to give medicines after a kidney transplant to elderly patients. It compares standard treatment with a different combination of drugs to see which works best for protecting the new kidney and keeping patients healthy.
Netherlands · Belgium - recruiting
Non-invasive Evaluation of Graft Condition in Adult Patients With Kidney Transplant Using Ultrasound Localization Microscopy and Multispectral Optoacoustic Tomography
This study uses new, gentle scanning methods (ULM and MSOT) to check how well a transplanted kidney is working. The aim is to see if these scans can reduce the need for painful kidney biopsies in the future.
Germany - recruiting
Expanding the Scope of Post-transplant HLA-specific Antibody Detection and Monitoring in Renal Transplant Recipients
This study is testing a new blood test for kidney transplant patients. It aims to find hidden antibodies that can damage the new kidney. Researchers also want to see if older patients are better protected against rejection and if we can predict who will develop these antibodies.
United Kingdom - recruitingPHASE3
Double-blind, Randomized, Placebo-controlled, Multicenter Study to Evaluate the Efficacy and Safety of Ravulizumab Administered Intravenously in Adult Participants at High Risk of Delayed Graft Function After Kidney Transplantation
This study looks at a new medicine called ravulizumab for adults receiving a kidney transplant from a deceased donor. It aims to see if this medicine can help their new kidney start working well faster, reducing the need for dialysis after the operation.
United States · Argentina · Australia - ongoing, recruitingPhase I and Phase II (Integrated)- Bioequivalence Study
A phase I/II study to assess the safety, tolerability, pharmacokinetics, pharmacodynamics and efficacy of FR104, a novel antagonist pegylated anti-CD28 Fab’ antibody fragment in de novo renal transplant patients
This study is testing a new medicine, FR104, for people who have recently had a kidney transplant. We want to see if it's safe, how well the body handles it, and if it helps prevent problems after the transplant. It's an early stage of testing this new treatment.
France - authorisedTherapeutic use (Phase IV)
MULTICENTER, RANDOMIZED STUDY TO EVALUATE THE EFFICACY OF INDIVIDUALIZATION OF IMMUNOLOGICAL RISK BASED ON SELECTIVE BIOMARKERS (HLA EPLETH DISPARITY AND IFN-γ ELISPOT) TO OPTIMIZE IMMUNOSUPPRESSIVE TREATMENT IN LIVING DONOR KIDNEY TRANSPLANT PATIENTS (BIOIMMUN)
This study looks at how to best adjust medicines after a kidney transplant from a living donor. It aims to find the right amount of medicine for each patient to prevent their body from rejecting the new kidney, using special tests to guide treatment.
Spain