End-stage Liver Disease (ESLD) research hub
4 indexed studies · 2 currently recruiting
- active not recruitingPHASE1, PHASE2
RTX001 Autologous Engineered Macrophages for Liver Cirrhosis
This study looks into a new treatment called RTX001 for severe liver disease like cirrhosis. It's made from your own cells and aims to reduce inflammation and scarring in the liver. This is the first time it will be tested in people to see if it's safe and effective.
Spain · United Kingdom - recruitingNA
Comparison of Inflammatory Profiles and Regenerative Potential in Alcoholic Liver Disease
This study compares how inflammation and liver repair differ in people with liver damage caused by alcohol. It looks at those with sudden severe alcoholic hepatitis, those with long-term alcoholic cirrhosis, and healthy people to understand these conditions better.
France - recruiting
Liver Transplantation in Patients With CirrHosis and Severe Acute-on-Chronic Liver Failure: iNdications and outComEs
This study looks at how well people with severe liver disease (ACLF) do after a liver transplant compared to those with less severe liver disease. It also checks why some people with ACLF don't get a transplant and how they fare.
United States · Argentina · Australia - active not recruitingPHASE1, PHASE2
Safety and Clinical Activity of QEL-001 in A2-mismatch Liver Transplant Patients
This study looks into a new treatment called QEL-001 for people who have had a liver transplant. The aim is to see if QEL-001, made from the patient's own cells, can help prevent the body from rejecting the new liver, especially when usual anti-rejection medicines are reduced or stopped.
Belgium · Spain · United Kingdom