Research.Patient.info
Locally advanced squamous cell carcinoma of the head and neck research hub
2 indexed studies · 0 currently recruiting
- ongoing, recruitingTherapeutic confirmatory (Phase III)
A double-blind randomized, Phase III study of radiotherapy combined with cetuXimab + Xevinapant compared to radiotherapy combined with cetuximab (Standard of care) + placebo in patients with Locally advanced (LA) squamous cell carcinoma of the head and neck (SCCHN), unfit for high-dose cisplatin (XXL study)
This study compares a new drug, xevinapant, plus standard treatment for an advanced form of head and neck cancer. Researchers want to see if adding xevinapant helps patients live longer without their cancer getting worse, compared to the standard treatment alone.
France - ongoing, recruitingHuman Pharmacology (Phase I)- Other
Phase 1b safety study of xevinapant, weekly cisplatin, and radiotherapy in participants with unresected LA SCCHN
This study is looking at a new treatment for advanced head and neck cancer. It combines a new drug called xevinapant with standard chemotherapy (cisplatin) and radiotherapy to see if it's safe and how well it works together.
Belgium · Spain