Metastatic Pancreatic Adenocarcinoma research hub
4 indexed studies · 3 currently recruiting
- recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
A study to compare Onivyde manufactured at two different production sites in adult participants with advanced cancer in the pancreas
This study is looking at a cancer medicine called Onivyde for advanced pancreatic cancer. Researchers want to check if Onivyde made in two different factories works in the same way in the body. It's a very early stage study for adults.
Spain · Hungary · Italy - recruitingTherapeutic confirmatory (Phase III)
An open-label, randomised, multicentre, phase III study of irinotecan liposome injection, oxaliplatin, 5-fluorouracil/leucovorin versus nab-paclitaxel plus gemcitabine in subjects who have not previously received chemotherapy for metastatic adenocarcinoma of the pancreas
This study is testing a new combination of treatments for advanced pancreatic cancer that hasn't been treated with chemotherapy before. It compares a new drug mix (irinotecan liposome, oxaliplatin, 5-fluorouracil/leucovorin) against a standard treatment (nab-paclitaxel, gemcitabine) to see which helps people live longer.
Spain - active not recruitingPHASE2
Gemcitabine Hydrochloride and Cisplatin With or Without Veliparib or Veliparib Alone in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer
This study looks at new ways to treat pancreatic cancer that has spread. It compares standard chemotherapy with or without a new drug called veliparib. We're testing if adding veliparib helps stop cancer growth, especially in people with specific genetic changes.
United States · Canada · Israel - recruitingPHASE3
A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer
This study is testing a new drug called setidegrasib for people in the UK with advanced pancreatic cancer. It's for those whose cancer has spread and has a specific gene change (KRAS G12D). The study wants to see if adding setidegrasib to standard chemotherapy helps people live longer and feel better.
United States · China · Japan