- recruiting
Real-life Evaluation of WEGOVY (Semaglutide) Treatment in Adults With Monogenic Obesity (ObGeSema)
This study looks at how well the medicine Wegovy (semaglutide) works for adults with a rare genetic type of obesity called monogenic obesity. Researchers want to see if it's as effective for them as it is for people with more common obesity.
France - authorisedTherapeutic confirmatory (Phase III)
An Open-Label Study of Mibavademab (REGN4461), a Leptin Receptor Agonist, for the Treatment of Monogenic Obesity Due to Biallelic Loss of Function Variants of the LEP Gene
This study is looking at a new medicine called mibavademab for people with a specific type of genetic obesity. It aims to see how well the medicine helps reduce body weight and improve other related health measures over time.
Germany - recruiting
Efficacy of Semaglutide s.c. Once-weekly on Weight Loss and Management in Adolescents With Monogenic Obesity in Clinical Practice
This study looks at how a weekly injection called semaglutide helps teenagers aged 12 to 21 with a specific type of genetic obesity. Researchers will see how it affects their weight, hunger, mood, and overall well-being over 68 weeks.
France · Germany · Netherlands