- ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Bioequivalence of Vortioxetine 20 mg Film-Coated Tablets in Healthy Participants Under Fasting Conditions
This study is testing a new version of a depression medicine called vortioxetine. We want to see if it works the same way in the body as the original medicine. Healthy volunteers will take a single dose under fasting conditions to help us understand this.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Bioequivalence of Tofacitinib 10 mg Film-Coated Tablets versus Xeljanz® 10 mg Film-Coated Tablets in Healthy Subjects Under Fasting Conditions
This study is testing if a new version of a 10mg "tofacitinib" tablet works the same way in the body as the existing Xeljanz® 10mg tablet. It's for healthy adults and helps ensure new medicines are just as effective.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Bioequivalence of Betis®10 mg Film-Coated Tablets versus Clozan 10 mg tablets in Healthy Subjects
This study compares a new medicine called Betis 10mg with an existing medicine called Clozan 10mg. It's for healthy adults and checks if both medicines work the same way in the body. It helps ensure new medicines are just as effective.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Bioequivalence of Amoxicillin and Clavulanic Acid 500 mg/125 mg Film-Coated Tablets in Healthy Participants Under Fed Conditions.
This study looks at how well different versions of a common antibiotic, Amoxicillin and Clavulanic Acid, are absorbed by healthy adults after they've eaten. It helps make sure new versions work just like existing ones.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Bioequivalence of Tofacitinib 10 mg Film-Coated Tablets versus Xeljanz® 10 mg Film-Coated Tablets in Healthy Subjects Under Fed Conditions
This study checked if a new version of the arthritis medicine Tofacitinib works the same way in the body as the original Xeljanz® tablets. It involved healthy people taking the medicine with food to see how it was absorbed.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Other
Pharmacokinetics and the Effect of Food on the Pharmacokinetics of TW102 in Healthy Subjects.
This study is looking at how a new medicine, TW102, works in the body of healthy volunteers. We want to see how much of the medicine gets into the blood and how food might change this. It's a very early study to learn more about TW102.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Comparative Bioavailability of Cabozantinib Film-Coated Tablets in Healthy Participants Under Fasting Conditions
This study is looking at how a medicine called cabozantinib is absorbed by the body. This is a very early-stage study involving healthy volunteers to see how the new tablet form compares to current forms of the medicine.
Portugal - authorisedHuman Pharmacology (Phase I)- Bioequivalence Study
Bioequivalence study of two sulodexide preparations: Sulodexide Intexo 250 LRU and Vessel Due F 250 LRU cps
This study is comparing two versions of a medicine called sulodexide to make sure they work the same way in the body. It's for healthy adults and helps ensure that different brands of the same medication are equally effective.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Bioequivalence of Lisdexamfetamine dimesylate 70 mg Capsules in Healthy Participants Under Fasting Conditions.
This study is checking if a new version of the medicine lisdexamfetamine dimesylate 70 mg works the same as the original. It's for healthy people, not those with a specific illness, and they won't eat before taking the medicine.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Bioequivalence of Ruxolitinib 20 mg Tablets in Healthy Participants Under Fasting Conditions.
This study is looking at a new version of a medicine called Ruxolitinib. It's for healthy adult volunteers to check if the new version works the same way as the original when taken on an empty stomach. This helps ensure medicines are safe and effective.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Bioequivalence of Lisdexamfetamine dimesylate 10 mg/mL Oral Solution in Healthy Participants Under Fasting Conditions.
This study is testing a new liquid version of a common medicine called lisdexamfetamine. Researchers want to see if this liquid medicine works the same way as the usual tablet form in healthy adults. It's for people who are generally well and will involve a few visits.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Other
Comparative Pharmacokinetic of S221237 Tablets in Healthy Participants Under Fed Conditions
This study is looking at how a new medicine, called S221237, is handled by the body in healthy men when taken with food. It's an early-stage study to understand the drug better, not to treat any illness.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Bioequivalence of Calcifediol monohydrate 0.266 mg Soft Capsules in Healthy Participants Under Fasting Conditions.
This study looks at a new vitamin D medicine (Calcifediol monohydrate) in healthy people. It checks if the new capsules deliver the medicine into the body in the same way as existing versions, helping to ensure they work correctly and are safe.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Other
Drug-Drug Interaction between Empagliflozin 25 mg Film-Coated Tablets and Alogliptin 25 mg Film-Coated Tablets in Healthy Participants Under Fasting Conditions
This study is looking at how two common diabetes medications, empagliflozin and alogliptin, interact when taken together. It's for healthy adults to see if combining them causes any unexpected effects.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Other
Drug-Drug Interaction between Alogliptin 25 mg Film-Coated Tablets and Empagliflozin 25 mg Film-Coated Tablets in Healthy Participants Under Fasting
This study looks at how two diabetes medications, Alogliptin and Empagliflozin, interact when taken together by healthy people. It's a small, early-stage study to understand how the body handles these drugs when used at the same time.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Bioequivalence of One Tablet of Gliclazide MR 120 mg (S005190) and Two Tablets of Gliclazide MR 60 mg (Diamicron® MR) in Healthy Participants under Fasting Conditions.
This study looks at how your body uses two different versions of a diabetes medicine called Gliclazide MR. It wants to see if one 120mg tablet works the same as two 60mg tablets. Healthy volunteers will take the medicine after not eating for a while.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Other
Multiple-Ascending Doses of 2-Methoxyestradiol in Healthy Non-Pregnant Female Participants.
This study is looking for healthy women to test a new medicine called 2-Methoxyestradiol. It's a very early study to see how the medicine works in the body and if it's safe at different doses. Participants don't have any medical conditions.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Bioequivalence of One Tablet of Gliclazide MR 90 mg (S005190) and One and a Half Tablets of Gliclazide MR 60 mg (Diamicron® MR) in Healthy Participants under Fed Conditions.
This study is looking at two different forms of a diabetes medicine called Gliclazide MR. We want to see if a 90mg tablet works in the same way as one and a half 60mg tablets when taken after food by healthy people. This helps confirm how medicines are absorbed.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Bioequivalence of Ruxolitinib 25 mg Tablets in Healthy Participants Under Fasting Conditions
This study is testing a new version of a medication called ruxolitinib in healthy adults. We want to see if the new tablet works the same way as the original. Participants will be healthy and take the medicine on an empty stomach.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Other
Investigation of Drug-Drug Interactions between LVDS (Levonorgestrel Vaginal Delivery System) and Miconazole in Healthy Female Participants.
This study is looking into how a hormone-releasing vaginal ring (LVDS) interacts with a common anti-fungal cream (miconazole) in healthy women. It helps us understand if using both at the same time changes how they work.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Bioequivalence of Lenvatinib 10 mg Capsules versus Lenvima® 10 mg Capsules in Healthy Participants Under Fed Conditions
This study is checking if a new version of the Lenvima® 10 mg capsule works the same way as the original in healthy people. They will receive the capsules after eating to see how the body handles them. It's an important step before a new medicine can be used.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Bioequivalence of Cinnarizine/Dimenhydrinate 20 mg/40 mg Tablets in Healthy Participants Under Fed Conditions.
This study is checking if a new version of combination tablets for dizziness and nausea works the same as an existing one. Healthy adults will take the tablets with food to see how the body absorbs the medicine. It's a pharmacy study, not a treatment trial.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Bioequivalence of Amoxicillin and Clavulanic Acid 250 mg/62.5 mg/5 mL Powder for Oral Suspension versus Augmentin® Forte 250 mg/62.5 mg/5 mL Powder for Oral Suspension in Healthy Participants Under Fed Conditions
This study is looking at a new version of a common antibiotic. We want to see if it works the same way in the body as the original. Healthy adults will take the medicine after eating, so we can compare how well it's absorbed.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Comparative Bioavailability of Teriflunomide 14 mg Film-Coated Tablets: A Single-Dose, Open-Label, Randomized, Two-Sequence, Two-Treatment, Two-Period Crossover Study in Healthy Subjects Under Fasting Conditions.
This study is looking at how a new version of teriflunomide 14mg tablets is absorbed in healthy men. It aims to see if the new tablet works in the same way as the current one. Participants will take the medicine once and be checked closely.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Bioequivalence of Etonogestrel 68 mg Implant in Healthy Pre-Menopausal, Nonpregnant Female Subjects.
This study is testing a new way to give a contraceptive (birth control) medicine called etonogestrel. Researchers want to make sure this new implant works the same as the current one, in healthy women who are not pregnant and haven't gone through menopause.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Bioequivalence of Metamizole Sodium 500 mg Film-Coated Tablets in Healthy Participants Under Fasting Conditions.
This study is checking if a new version of the painkiller Metamizole works in the same way as an older version in healthy volunteers. It will help ensure the new tablet is just as good.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Bioequivalence of One Tablet of Gliclazide MR 120 mg (S005190) and Two Tablets of Gliclazide MR 60 mg (Diamicron® MR) in Healthy Participants under Fed Conditions.
This study is checking if a new 120mg gliclazide tablet works the same way in your body as two older 60mg tablets. It's for healthy volunteers and helps ensure new medicines are just as effective as existing ones, especially when taken with food.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Bioequivalence of Linagliptin 5 mg Film-Coated Tablets in Healthy Participants Under Fasting Conditions
This study is testing if a new version of the diabetes medicine, Linagliptin, works the same way as the original. Healthy adults take the medicine on an empty stomach, and researchers check how it's absorbed into their bodies. It's an early-stage study to make sure the new medicine is just as effective.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Single dose, open-label, laboratory blinded, randomized, 2-treatment, 2-period, 2-sequence, crossover, pivotal study to assess the relative bioavailability of Test Product Naproxen sodium 660 mg modified release tablets to Reference Product Actromadol 660 mg Modified-Release tablets in healthy adult male and female subjects under fed conditions.
This study compares a new painkiller, similar to Actromadol, in healthy adults. We want to see if the new tablet works in the body similarly to the existing one after a meal. It's an important step before making new medicines widely available.
Czechia - ongoing, recruitingHuman Pharmacology (Phase I)- First administration to humans
Single-Ascending Doses of 2-Methoxyestradiol in Healthy Non-Pregnant Female Subjects.
This study is testing a new medicine called 2-Methoxyestradiol in healthy women for the very first time. We want to see how safe it is and how the body handles it at different small doses. It's an early step in developing new treatments.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Other
Investigate Drug-Drug Interactions between LVDS (Levonorgestrel Vaginal Delivery System) and Tampons and Lubricants in Healthy Female Participants
This study is looking at how a new type of contraception, a vaginal ring for women, works when used with tampons and lubricants. Researchers want to make sure it's safe and effective for everyday use.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Comparative Bioavailability of Diclofenac 2.32% Gel in Healthy Adult Subjects
This study is checking how well a pain-relief gel called diclofenac 2.32% gets into the body. It's for healthy adults and helps us understand if different versions of the gel work the same way. It's an early-stage study, not testing a new treatment.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Bioequivalence of Lenvatinib 10 mg Capsules in Healthy Participants Under Fasting Conditions
This study is testing if a new version of the cancer medicine Lenvatinib works the same way as the original. It involves healthy adults taking a single dose on an empty stomach to see how it's absorbed by the body.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Evaluating Bioequivalence of a Fixed Dose Combination versus Individual Tablets of Bempedoic Acid, Ezetimibe, and Atorvastatin.
This study is testing if a new combined pill works the same way in your body as taking three separate pills for lowering cholesterol. It's for healthy adults and is a very early stage of research to make sure the combined pill is just as effective.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Bioequivalence of Tofacitinib 10 mg Film-Coated Tablets in Healthy Subjects Under Fasting Conditions.
This study is checking if a new version of the arthritis drug Tofacitinib works the same way as the original. Healthy volunteers will take the new tablet to see how their bodies absorb it, helping ensure new medicines are just as effective and safe.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Comparative Bioavailability of Ruxolitinib 20 mg Film-Coated Tablets in Healthy Participants Under Fasting Conditions.
This study looks at how well a new tablet form of a medicine called ruxolitinib is absorbed by the body. It involves healthy adult volunteers who will take the medicine on an empty stomach. The main goal is to make sure the new tablet works the same way as the original medicine.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Bioequivalence of Mirabegron 50 mg Prolonged-Release Tablets in Healthy Participants Under Fasting Conditions.
This study is testing a new version of a 50mg mirabegron tablet to see if it works the same as the original. It's for healthy adults and helps make sure medicines are reliable for patients.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Other
Safety and tolerability of medicated chewing gum with sodium alginate, calcium carbonate and sodium bicarbonate.
This study is looking at a new chewing gum that contains three common ingredients: sodium alginate, calcium carbonate, and sodium bicarbonate. We want to find out if it's safe to use and if people can tolerate it well. This is a very early stage of testing in healthy adults.
Portugal - authorisedHuman Pharmacology (Phase I)- Bioequivalence Study
Bioequivalence of Lisdexamfetamine dimesylate 10 mg Capsules in Healthy Participants Under Fasting Conditions.
This study is testing a new version of a medicine called lisdexamfetamine dimesylate 10 mg capsules. It's for healthy adults and checks if the new version works the same way as the original when taken without food. It helps make sure new medicines are just as effective.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Bioequivalence of Ulipristal 30 mg Tablets in Healthy Subjects Under Fed Conditions
This study is checking if a new version of ulipristal 30 mg tablets works the same way as an existing one in healthy women. It's a very early-stage study to make sure the body uses the medicine in the same way when taken with food.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Bioequivalence of Etonogestrel 68 mg Implant in Healthy Pre-Menopausal, Nonpregnant Female Subjects.
This study is testing a new version of the etonogestrel implant, a type of birth control. We want to see if it works the same way as the already approved one. It's for healthy women who are not pregnant and haven't gone through menopause.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Bioequivalence of Lisdexamfetamine dimesylate 20 mg Capsules in Healthy Participants Under Fasting Conditions.
This study is testing a new version of a medication called Lisdexamfetamine dimesylate. It's to make sure the new version works the same as the original. Healthy adults will take the medication on an empty stomach, and doctors will check how their bodies use it.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Bioequivalence of Vortioxetine 5 mg Film-Coated Tablets in Healthy Participants Under Fasting Conditions.
This study looks at how a new version of the antidepressant medicine called vortioxetine gets into the body. It checks if the new tablet works the same way as the original in healthy volunteers, to make sure it's just as effective.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Other
Evaluation of the Effect of Food, Itraconazole, and Rifampicin on the Single-Dose Pharmacokinetics of Naronapride.
This study is gathering information on how a new medicine called Naronapride works in healthy people. We want to see how food and other common medicines affect it. This helps us understand the best way to use Naronapride in the future.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Evaluating Bioequivalence of a Fixed Dose Combination versus Tablets of Bempedoic Acid / Ezetimibe and Rosuvastatin.
This study is checking if a new combined pill for cholesterol works the same way as taking the medicines separately. It's for healthy adults to make sure the combined pill is just as good.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Comparative Bioavailability of Empagliflozin 25 mg Film-Coated Tablets: A Single-Dose, Open-Label, Randomized, Two-Sequence, Two-Treatment, Two-Period Crossover Study in Healthy Subjects Under Fasting Conditions.
This study compared two versions of a 25 mg empagliflozin tablet in healthy volunteers. It checked if they delivered the same amount of medicine into the body after a single dose, helping ensure consistent drug effects for patients.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Other
Evaluation of the Effect of Itraconazole, Quinidine and Rifampicin on the Single-Dose Pharmacokinetics of ZED1227
This study is testing how a new medicine, ZED1227, works in the body when taken with common medications like itraconazole, quinidine, or rifampicin. We want to see if these other medicines change how ZED1227 is handled by the body.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Bioequivalence of Etonogestrel 68 mg Implant in Healthy Pre-Menopausal, Non-Pregnant Female Participants.
This study is testing a new version of the etonogestrel implant, a type of birth control. We want to see if the new implant works the same way as the original. It's for healthy women who are not pregnant and haven't gone through menopause.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Bioequivalence of Etonogestrel 68 mg Implant in Healthy Pre-Menopausal, Non-Pregnant Female Participants.
This study is testing a new version of the Etonogestrel implant, a type of birth control. It's for healthy women who are able to get pregnant but aren't currently. The aim is to see if the new implant works the same way as the original.
Portugal - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Bioequivalence of Canagliflozin 300 mg Film-Coated Tablets in Healthy Participants Under Fasting Conditions.
This study is testing a new version of a diabetes medicine called Canagliflozin. It wants to see if the new tablet works in the same way as the original one in healthy adults who haven't eaten. It's a key step to make sure new medicines are safe and effective.
Portugal