No therapeutic indication in the current trial with healthy volunteers. research hub
14 indexed studies · 13 currently recruiting
- authorisedHuman Pharmacology (Phase I)- Bioequivalence Study
Evaluation of the bioequivalence of two intravaginal gel preparations containing 90 mg progesterone
This study tests two different vaginal gels that contain progesterone, a natural hormone. Researchers want to see if a new gel delivers the same amount of medicine into the bloodstream as an approved gel. It involves healthy adult women and helps make sure different medicine brands work equally well.
Bulgaria - recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Evaluation of bioequivalence of two products containing 400 mg ibuprofen and 100 mg caffeine: Ibuprofen / Caffeine 400 mg / 100 mg coated granules (Test) vs. Thomapyrin TENSION DUO, 400mg / 100mg Filmtabletten (Reference). A monocentric, open, randomized, single dose, two-period, crossover trial in healthy volunteers
This study is comparing two ibuprofen and caffeine pain relief medicines to see if they work in the same way in the body. It involves healthy adult volunteers taking single doses of each medicine to check how they are absorbed.
Bulgaria - recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
A study to investigate the similarity of two different Tiotropium inhalers in healthy volunteers.
This study is looking at two different inhalers that contain the medicine Tiotropium to see if they work in a very similar way. Healthy volunteers will help us compare how their bodies handle the medicine from each inhaler.
Bulgaria - recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Evaluation of bioequivalence of two products containing 50 mg dimenhydrinate: Dimenhydrinate 50 mg (Test) vs. Vomex A 50 mg Lösung zum Einnehmen im Beutel (Comparator). A monocentric, open, randomized, single dose, two-period, crossover trial in healthy volunteers
This study compared two versions of a 50mg dimenhydrinate medicine, often used for motion sickness. It checked if a new version worked in the same way as an existing one, by giving a single dose to healthy adult volunteers and seeing how the body handled them.
Bulgaria - recruitingHuman Pharmacology (Phase I)- Other
Evaluation of the bioavailability of two transdermal gel preparations containing 0.1% w/w estradiol under fasting conditions: Estradiol/INTERMED gel 0.1% w/w (Test) vs. ESTREVA® 0.1%, gel (Comparator). A monocentric, open, randomized, single dose, two-period, crossover trial in healthy postmenopausal women
This study is comparing two oestrogen gels for women after menopause. It wants to see how well a new gel (Estradiol/INTERMED) is absorbed into the body compared to an existing one (ESTREVA®). Healthy women will take part to help us understand the gels better.
Bulgaria - recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Evaluation of the bioequivalence of two products containing esomeprazole under fed conditions: Esomeprazole-Syrup 40 mg dose (Test) vs. Nexium 40 mg (Comparator). An open, randomized, single dose, four-period, replicate, crossover trial in healthy volunteers
This study compares a new liquid version of a stomach acid medicine (esomeprazole) with the existing pill. It aims to check if both deliver the same amount of medicine to healthy volunteers' bodies after eating. This helps ensure new medicines work just as well.
Bulgaria - recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Evaluation of the bioequivalence of two products containing esomeprazole under fasting conditions: Esomeprazole-Syrup 40 mg dose (Test) vs. Nexium 40 mg (Comparator). An open, randomized, single dose, four-period, replicate, crossover trial in healthy volunteers
This study compares a new liquid form of esomeprazole with Nexium, an existing medication. We want to see if the new liquid medicine is absorbed by the body in the same way as Nexium. We are looking for healthy adult volunteers to take part.
Bulgaria - recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Single dose oral bioequivalence study of Cladribine 10 mg Tablets and Mavenclad® 10 mg tablets (Cladribine) in healthy adult human subjects under fed conditions
This study is testing a new version of cladribine tablets to see if it works the same way as an existing one. We need healthy adult men to take a single dose of the medication to help us compare them.
Bulgaria - recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Evaluation of bioequivalence of two products containing 600 mg ibuprofen: Ibuprofen Sopharma 600 mg film-coated tablets (Test) vs. Brufen 600 mg film-coated tablets (Comparator). A monocentric, open, randomized, single dose, two-period, crossover trial in healthy volunteers
This study compared two ibuprofen tablets to see if they work the same way in the body. It involved healthy adult volunteers taking a single dose of each tablet at different times to check for similar absorption.
Bulgaria - recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Bioavailability study with naloxone hydrochloride in healthy volunteers
This study is looking at a medicine called naloxone hydrochloride. It's a very early stage trial, checking how the body uses this medicine in healthy volunteers. The aim is to understand how well the body absorbs and uses the drug.
Bulgaria - recruitingHuman Pharmacology (Phase I)- Other
A Pilot Open-label, Randomized, Crossover, Comparative Bioavailability Study of Levodopa Administered via Levodopa Cyclops™ (test product) Relative to INBRIJA® (reference product) in Healthy Adult Subjects
This study is testing a new way to give a Parkinson's medicine, levodopa, to see how well the body takes it in compared to an existing inhaler. It's an early-stage study in healthy adults.
Bulgaria - recruitingHuman Pharmacology (Phase I)- Other
Evaluation of the bioavailability of two products containing esomeprazole under fasting and fed conditions: Esomeprazole-Syrup 40 mg dose (Test) vs. Nexium 40 mg (Comparator). A monocentric, open, randomized, single dose, four-period, crossover trial in healthy volunteers
This study is comparing a new liquid version of a common stomach medicine (esomeprazole) with the existing pill form. It's to see how well the body absorbs the liquid medicine when taken with or without food. Healthy volunteers are helping with this simple first-stage trial.
Bulgaria - recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Bioequivalence of Cladribine 10 mg from two different products
This study is looking at two versions of a drug called cladribine to see if they work the same way in the body. It’s for healthy men, not patients, to help develop a treatment for a type of multiple sclerosis (MS).
Bulgaria - recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
An open label, randomized, four-period, four-sequence single dose, crossover trial in healthy volunteers to determine the relative bioavailability of Dimenhydrinate 50 mg (Test) administered with and without water vs. Vomex A 50 mg Lösung zum Einnehmen im Beutel (Reference 1) and Biodramina 50 mg Comprimidos (Reference 2)
This study is testing how two different anti-sickness medications, similar to those you might take for travel sickness, are absorbed by the body. It compares a new version of dimenhydrinate with two existing ones, checking if they work in the same way. Healthy volunteers are participating.
Bulgaria