- ongoing, recruitingTherapeutic confirmatory (Phase III)
Fentanyl effect on ventilatory pattern under sham postsurgical conditions – an exploratory study in healthy men and women – the FAME study
This study, called FAME, is looking at how a pain medicine called fentanyl affects breathing in healthy adults. Researchers want to understand its effects better to improve safety, especially after operations. It's a key step in understanding how this medicine works.
Netherlands - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A randomised, assessor-blinded, controlled, healthy volunteer, Phase I study to assess skin irritation and sensitization potential of a novel 5% lidocaine medicated plaster
This study is testing a new 5% lidocaine plaster (a sticky patch with medicine) on healthy volunteers. We want to see if it irritates the skin or causes any allergic reactions. This is an early-stage study to check its safety on skin.
France - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A randomized, investigator masked pilot study to establish the experimental conditions and select the criteria to compare topical application of 2 methyl aminolevulinate creams: evaluation of protoporphyrin IX formation in the skin of healthy subjects.
This study is looking at how two different skin creams work. Researchers want to see which cream is better at causing a natural chemical, called protoporphyrin IX, to form in healthy skin. This helps them plan future studies on skin treatments.
France