- recruitingHuman Pharmacology (Phase I)- Other
A study investigating the safety, absorption, and elimination of RO7795068, a new compound that may potentially be used in the treatment of obesity
This early-stage clinical trial tests a new potential obesity medicine called RO7795068. Researchers want to see how safe it is and how the human body takes it in and removes it. The trial is open to adults aged 18 and over to help guide future treatments.
Netherlands - authorisedHuman Pharmacology (Phase I)- Other
A Study to See How a New Compound, Trontinemab Affects the Body and Whether Immune Signals Triggered by it Affect How Other Medicines are Processed
This early-stage study looks at a new drug called trontinemab in adult men. Researchers want to understand how it behaves in the human body. They also want to see if the body's natural immune response to the drug changes the way other everyday medicines are broken down.
Germany - recruitingHuman Pharmacology (Phase I)- Other
A Study to find out the safety, tolerability and interaction of drug with body (including the effect of Itraconazole on RO7268489) and also what the body does to RO7268489 after oral intake by healthy participants
This study is looking at a new medicine called RO7268489. We want to see how safe it is, how well people tolerate it, and what happens to the medicine in the body after someone takes it by mouth. We also want to see if another medicine, Itraconazole, changes how RO7268489 works.
Netherlands - recruitingHuman Pharmacology (Phase I)- Other
A study to assess the effect of gemfibrozil, itraconazole and phenytoin on levels of IPN60250 in the blood of healthy adult participant.
This study is looking at how certain medicines (gemfibrozil, itraconazole, and phenytoin) affect the levels of a new drug called IPN60250 in the blood. Healthy adults over 18 can take part. It's an early-stage study to understand how drugs interact.
Germany - recruitingHuman Pharmacology (Phase I)- Other
A study to assess the effects of efgartigimod on emasiprubart in healthy adult participants
This study is looking at how two new medicines, efgartigimod and emasiprubart, work in healthy adults. It's an early-stage study to understand how these medicines behave in the body, not to treat any specific illness yet.
Belgium - recruitingHuman Pharmacology (Phase I)- Other
Neurogenic inflammation upon AITC-induced TRPA1 activation
This study looks at how a natural chemical, similar to what makes mustard spicy, affects nerves in healthy men. Researchers want to understand how our bodies react to certain sensations. This helps scientists learn more about how our nerves work and react to irritation.
Belgium - recruitingHuman Pharmacology (Phase I)- First administration to humans
A Study to Learn How Safe Different Doses of NTS-521 are, What the Amount of NTS-521 in the Body is Over a Period of Time, and What the Effects of NTS-521 on the Body and the Body on NTS-521 are in Adult and Elderly People Receiving Single and Multiple Doses of NTS-521 via an Infusion Directly into a Vein
This study is the first time a new medicine, NTS-521, will be given to people. It aims to check what doses are safe, how much of the medicine stays in the body over time, and how the body reacts to it when given through a drip.
Belgium - recruitingHuman Pharmacology (Phase I)- Other
A study investigating the safety, absorption, and elimination of RO7795081, a new compound that may potentially be used in the treatment of type 2 diabetes and weight control
This study is looking at a new medicine called RO7795081. It's hoped this medicine might help people with type 2 diabetes and those trying to manage their weight. Researchers want to see if it's safe, how the body uses it, and how it leaves the body.
Netherlands - recruitingHuman Pharmacology (Phase I)- Other
A study comparing different RO7269162 capsules and investigating the effect of food on the uptake, breakdown, and elimination of RO7269162 in Healthy Participants
This study is testing a new medicine, RO7269162, in healthy people. We want to see how different forms of the capsule work in the body and if food changes how the body uses the medicine. This helps us understand the best way to give the medicine in the future.
Netherlands - recruitingHuman Pharmacology (Phase I)- Other
A Study to Track How the Healthy Male Participants Handles the New Oral Drug RO7795081 for Weight Management and Diabetes
This study is testing a new oral drug, RO7795081, in healthy men. It's a very early stage trial looking at how their bodies handle the drug, which is being developed to help with weight and diabetes.
Netherlands