Not applicable, healthy volunteers research hub
8 indexed studies · 8 currently recruiting
- recruitingHuman Pharmacology (Phase I)- Other
A single dose, randomized, double-blind 2-arm parallel-group study to compare the pharmacokinetics, immunogenicity, and safety for PB016 versus US-licensed Entyvio® after subcutaneous administration in healthy participants
This study tests a new medicine called PB016 in healthy adult volunteers. PB016 is designed to be a biosimilar, meaning it aims to work just like an existing medicine called Entyvio. Researchers want to compare how a single injection under the skin is absorbed, processed, and tolerated by the body.
Germany - recruitingHuman Pharmacology (Phase I)- Other
A SINGLE-CENTER, OPEN-LABEL, TWO-PERIOD STUDY TO INVESTIGATE THE EFFECT OF MULTIPLE DOSE ITRACONAZOLE, A STRONG CYP3A INHIBITOR, ON THE PHARMACOKINETICS OF A SINGLE 30 MG DOSE OF RO7269162 IN HEALTHY PARTICIPANTS
This study looks at how a new medicine, RO7269162, works in the body when taken with another medicine, Itraconazole. It needs healthy volunteers to understand how these medicines interact with each other. This is an early-stage study to help us learn more about the new medicine.
Netherlands - recruitingHuman Pharmacology (Phase I)- Other
A Phase 1, Randomized, Open Label, Single-Dose Crossover Study to Assess the Relative Bioavailability, Food Effect, and Safety of Capsule Formulations of INF904.
This study is looking at a new medicine called INF904. We want to see how well different forms of this medicine get into the body and if food changes that. It's for healthy adults and is an early-stage study to check safety.
Netherlands - recruitingHuman Pharmacology (Phase I)- Other
A trial to learn about how multiple doses of itraconazole change how AZD5004 moves throughout the body over time in healthy adults and how multiple doses of AZD5004 change how ethinyl estradiol and levonorgestrel move throughout the body overtime in healthy female adults
This study looks at how a new drug, AZD5004, interacts with a common anti-fungal medicine (itraconazole) and with common birth control pills (ethinyl estradiol and levonorgestrel). It's for healthy adults and helps us understand how these medicines work together in the body.
Germany - recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
A RANDOMIZED, DOUBLE-BLIND, THREE-PART, TWO-PERIOD, TWO-SEQUENCE, SINGLE-DOSE, CROSS-OVER STUDY TO COMPARE THE PHARMACOKINETICS (PK), SAFETY AND IMMUNOGENICITY PROFILE OF MB04 (PROPOSED ETANERCEPT BIOSIMILAR), EU-SOURCED ENBREL® AND US-LICENSED ENBREL® IN HEALTHY MALE VOLUNTEERS.
This study compares a new version of a common medicine (MB04) to the original medicine (Enbrel) in healthy men. It checks how the body handles the medicine and for any side effects, to make sure the new version works the same way.
Netherlands - recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
A Phase I, Randomized, Partial Double-blind, Single dose, 3-Way Cross-over Study to Assess the Lung Exposure Bioequivalence of Budesonide, Glycopyrronium, and Formoterol for BGF MDI HFO Compared with BGF MDI HFA Using an AeroChamber Plus Flow-Vu Spacer and to Compare the Lung Exposure of BGF MDI HFO with a Spacer to BGF MDI HFO without a Spacer
This study looks at a new inhaler for breathing problems. We're testing how much of the medicine reaches the lungs when used with or without a spacer, compared to a current inhaler. It's for healthy adults to make sure the medicine works as expected.
Germany - recruitingHuman Pharmacology (Phase I)- Other
A study to investigate the effect of ASTX660 (tolinapant) on the pharmacokinetics of substrates of OCT1, OCT2, and MATE1 in healthy volunteers
This study is looking at how a new medicine, ASTX660 (also called tolinapant), moves through the body of healthy volunteers. We want to see how it might affect other medicines someone could be taking, specifically how their body handles them.
Germany - recruitingHuman Pharmacology (Phase I)- Other
A trial to learn how much budesonide, glycopyrronium, and formoterol fumarate (BGF) gets into and moves throughout the body when it is taken with hydrofluoroolefin (HFO) compared to when it is taken with hydrofluoroalkane (HFA) in healthy adults
This study is looking at how a new inhaler works. It compares two ways of delivering the same medicine to healthy adults: one using a new propellant (HFO) and another using a common propellant (HFA). We want to see how the medicine enters and moves through the body.
Germany