Obesity, Overweight, Osteoarthritis, Knee research hub

J1I-MC-GZBJ: A Master Protocol to Investigate the Efficacy and Safety of LY3437943 Once Weekly in Participants Without Type 2 Diabetes Who Have Obesity or Overweight: A Randomized, Double-Blind, Placebo-Controlled Trial (TRIUMPH-1); J1I-MC-GOA1: Indication-Specific Appendix (ISA2) for participants with knee osteoarthritis (OA)

This study is looking at a new medicine called Retatrutide for adults who are overweight or have obesity. It also specifically looks at people with knee arthritis. The main goals are to see how much it helps with weight loss and how well it reduces knee pain.