- authorisedTherapeutic use (Phase IV)
Botulinum toxin in open abdomen closure. A multicentric randomized controlled single-blind clinical trial to evaluate the efficacy of early administration of botulinum toxin for primary midline closure in patients with an open abdomen.
This study looks at using a medicine called botulinum toxin (Dysport) to help people with an 'open abdomen' close their tummy muscles. Researchers want to see if giving this medicine early helps bring the wound edges together, avoiding bigger operations.
Spain - recruiting
Effects of AbClo Fascial Approximation Device in Patients With Open Abdomen on Respiratory Mechanics
This study looks at how a device called AbClo, used after tummy surgery, affects patients' breathing. It checks how the device changes lung pressure and air volume, and if adjusting breathing machines helps to manage these changes.
Canada