- recruitingPhase I and Phase II (Integrated)- First administration to humans
Guided by Light: Optimizing Surgical Excision of Oral Cancer Using Real-time Fluorescence Imaging
This study looks at a new way to help surgeons remove oral (mouth) cancer more completely. It uses a special light to make the cancer glow during surgery, aiming to ensure all cancer cells are taken out and reduce the need for more operations later.
Netherlands - recruitingNA
Tolerance and Benefits of Mandibular Advanced Device for Snoring and Sleep Apnea in Oropharyngeal Cancer.
This study looks at how well a special mouthguard, called a Mandibular Advancement Device (MAD), works to help people with throat cancer who snore or stop breathing in their sleep. It checks if the device is comfortable and helpful.
Canada - recruitingNA
Mandibular Reconstruction Preplanning (ViPMR)
This study compares two ways to rebuild the jaw after cancer surgery: an advanced 3D planning method or the standard approach. Researchers want to see which method helps patients heal best and has fewer problems. It's for people having jaw surgery for oral cancer.
Canada - authorised (with conditions)Phase III and phase IV (Integrated)
Sentinel lymph node (SLN) detection in early oral cancer using Gallium-68-Tilmanocept PET/CT.
This study is looking at a new way to find if oral cancer has spread to nearby lymph nodes. It uses a special scan called a PET/CT with a harmless substance to see these nodes, comparing it to current methods.
Netherlands - not yet recruiting
Real-time Molecular Diagnosis of Oral Precancer
This study is testing a new device that uses a laser to scan inside the mouth to help find early signs of mouth cancer. The aim is to make diagnosing mouth cancer quicker and easier, potentially improving treatment success rates.
United Kingdom