Out-Of-Hospital Cardiac Arrest research hub
9 indexed studies · 5 currently recruiting
- active not recruitingNA
Emergency Resuscitative Endovascular Balloon Occlusion of the Aorta in Out of Hospital Cardiac Arrest
This study looks at using a special balloon device (REBOA) in the main artery to help people who have a sudden heart stop outside of hospital. It aims to see if this method is practical and helpful alongside standard emergency care to improve survival.
United Kingdom - recruiting
German Cardiac Arrest Registry
This study is gathering information on people in Germany who have a sudden heart stoppage outside of a hospital. It aims to understand why this happens and how best to treat it, to help improve care for patients in the future.
Germany - recruitingNA
Prehospital Resuscitation Intranasal Cooling Effectiveness Survival Study 2
This study looks at whether very early cooling, started by paramedics, can help people who have had a sudden heart stoppage outside of hospital. We want to see if it improves survival and brain recovery compared to keeping body temperature normal.
Austria · Belgium · Germany - active not recruitingNA
The PulsePoint Study
This study looks at whether the PulsePoint app helps people near a sudden heart attack (cardiac arrest) in public places give CPR or use a defibrillator sooner. Half of these emergencies will get an app alert, and half won't, to see which approach works best.
United States · Canada - not yet recruiting
Ambulance Clinicians' Experiences of Attending OHCA in Children
This study looks at how ambulance crews handle children's cardiac arrests outside hospitals. It aims to understand their challenges and experiences to improve care and support for both patients and the clinicians themselves.
United Kingdom - recruiting
Drone Delivery of Automated External Defibrillators to Lay Users (DAEDALUS): A Proof of Concept Study
This study is exploring using drones to deliver heart-starting devices (called AEDs) quickly to people having a cardiac arrest outside of a hospital. The aim is to see how well drone delivery works and if it can help more people survive.
United Kingdom - authorisedTherapeutic confirmatory (Phase III)
Impact of low dose epinephrine in the management of out-of-hospital cardiac arrest on neurological outcome: A multicenter randomized and double-blind trial (Low-EPI Study)
This study, called Low-EPI, is looking at whether a lower dose of adrenaline (epinephrine) given to people who have a sudden cardiac arrest outside of a hospital can help them recover better, especially with their brain function, compared to the usual dose. We want to see if it improves their health after 28 days.
France - active not recruitingNA
Effects of Sedation, TEmperature and Pressure After Cardiac Arrest and REsuscitation on Major Adverse Kidney Events (STEPCARE-MAKE)
This study looks at how different ways of caring for people after a heart attack affect their kidneys. It checks if particular levels of sedation, temperature control, and blood pressure targets can help prevent kidney problems.
Australia · Belgium · Estonia - recruitingNA
Cardiac Arrest Bundle of cARE Trial
This study looks at new technology to help people who have a sudden heart stop outside of hospital. It combines three devices to improve blood flow during CPR, hoping to boost survival rates and protect the brain. It's a pilot study to see if using these devices together is practical and helpful.
United Kingdom