Peripheral artery disease research hub
10 indexed studies · 4 currently recruiting
- recruitingPhase III
A study of the anti-inflammatory medication colchicine for people with blocked arteries of the legs
Peripheral arterial disease (PAD) causes narrowed blood vessels in the legs. This clinical trial is testing whether an anti-inflammatory tablet called colchicine can help protect arteries and reduce the risk of serious complications, such as heart attacks, strokes, and leg amputations, in people living with PAD.
United Kingdom · England · Argentina - recruiting
A study to test a home walking programme for people living with peripheral artery disease
This UK study tests a home walking programme called MOSAIC2 for people aged 50 and over with peripheral artery disease. It explores whether support from local GP surgeries and community clinics can help people walk further with less leg pain, helping the NHS improve care for circulation problems.
United Kingdom · England - authorisedTherapeutic confirmatory (Phase III)
A Master Protocol for a Phase 3, Multicenter, Randomized Study to Evaluate the Efficacy and Safety of REGN7508 and REGN9933, Monoclonal Antibodies Against Factor XI, in Participants with Recent Lower Extremity Revascularization for Symptomatic Peripheral Artery Disease (ROXI-PALISADE)
This clinical trial is testing new blood-thinning medicines for adults with peripheral artery disease who recently had a procedure to restore blood flow in their legs. Researchers want to find out if these medicines can prevent serious blood clots, heart attacks, and amputations without causing major bleeding problems.
Spain · Slovakia · Hungary - recruiting
Acotec DCB Post Market Clinical Follow-up
This study looks at how well a special balloon, coated with medicine, works for people with poor circulation in their legs. It aims to see if it's safe and effective in real-world use for helping improve blood flow and reduce leg pain.
Germany - active not recruiting
BIOTRONIK Dynetic-35 Stent for the Treatment of Peripheral Iliac Lesions
This study tested a new stent called Dynetic-35 to treat blockages in blood vessels in the pelvis, which can cause leg pain. It looked at how safe and effective this new stent was for people with Peripheral Artery Disease.
Austria · Belgium · France - active not recruitingPHASE3
VIRTUOSE : Efficiency of Sildenafil on the Absolute Claudication Distance of Peripheral Arterial Disease Patients With Intermittent Claudication.
This study investigates if sildenafil (commonly known as Viagra) can help people with Peripheral Artery Disease (PAD) walk further without pain. It's a large study comparing sildenafil to a dummy pill to see if it improves walking ability and quality of life.
France - active not recruitingNA
Trial to Assess the Safety and Efficacy of Sirolimus-Coated Balloon vs. Uncoated Standard Angioplasty for the Treatment of Below-the-knee Peripheral Arterial Disease
This study compares two ways to treat narrowed leg arteries: a standard balloon and a special balloon coated with medicine. It aims to see which is safer and works better for people with a serious leg condition called Peripheral Artery Disease.
Austria · Germany - recruitingNA
Motivating Physical Activity With Behavioural interVention and Electrical Stimulation Remotely in Intermittent Claudication
This study looks at new ways to help people with leg pain from poor circulation (Peripheral Artery Disease, or PAD) walk more easily. It combines remote physiotherapy with a pain-relief device called TENS to see if this helps people get more active at home.
United Kingdom - active not recruiting
Observational GORE® VIABAHN® Endoprosthesis With PROPATEN Bioactive Surface Global Registry
This study looks at how a special covered stent, called the GORE VIABAHN Endoprosthesis, performs in real-world patients. It helps doctors understand its safety and effectiveness for various conditions like common circulation problems, widening arteries, and injury repair.
Belgium · France · Germany - active not recruitingNA
SUCCESS (SelUtion, Safety, effiCaCy, hEalth economicS and promS) PTA Study
This study looks at a new treatment called SELUTION SLR, a special balloon for Peripheral Artery Disease. It checks how well it works and if it's safe in real-world patients. Doctors will also see how it affects people's health over five years.
Argentina · Germany · Greece