Primary membranous nephropathy research hub
9 indexed studies · 5 currently recruiting
- authorisedTherapeutic exploratory (Phase II)
Obinutuzumab induced decreases of PLA2Rab in MN: a pilot study
This study is looking at a new treatment called Gazyvaro (obinutuzumab) for a kidney disease called primary membranous nephropathy. It aims to see how well the medicine reduces certain antibodies (PLA2R antibodies) that cause the disease, and if it helps improve kidney function and quality of life.
Netherlands - ongoing, recruitingTherapeutic exploratory (Phase II)
Obinutuzumab for primary membranous nephropathy: a pilot study in patients with rituximab-resistant or rituximab-dependent nephrotic syndrome and in patients intolerant to rituximab (the ORION study)
This study looks at a new drug, Obinutuzumab, for a kidney disease called primary membranous nephropathy. It's for people whose disease hasn’t responded well to a common treatment called rituximab, or if they can’t take rituximab. We want to see how well it works and if it's safe.
Italy - recruitingPHASE2
A Study to Assess the Effect of Surovatamig in Adult Participants With Antibody-mediated Kidney Disease
This study is testing a new medicine, Surovatamig, for adults with a specific kidney disease called Primary Membranous Nephropathy. It will check how safe the medicine is, how well the body handles it, and if it helps treat the condition and prevent serious kidney problems.
United States · Belgium · France - recruitingPHASE2, PHASE3
Evaluation of Efficacy, Safety, and Tolerability of Povetacicept in Participants With Primary Membranous Nephropathy (pMN)
This study is testing a new medicine, povetacicept, for people with a kidney condition called primary membranous nephropathy (pMN). It aims to see how well it works, if it's safe, and if people can tolerate it compared to another treatment, tacrolimus.
United States · Australia · Brazil - recruitingPHASE2
Study of ALXN1920 in Adult Participants With Primary Membranous Nephropathy (PMN)
This study is looking at a new medicine called ALXN1920 to see if it can help adults with a kidney disease called Primary Membranous Nephropathy (PMN). Researchers want to find out if this medicine works better than a dummy treatment (placebo) for people at higher risk of their kidney disease getting worse.
United States · Argentina · Australia - recruitingPHASE3
A Study to Learn More About the Effects and Safety of Felzartamab Infusions in Adults With Primary Membranous Nephropathy (PMN)
This study looks at a new drug, felzartamab, for Primary Membranous Nephropathy (PMN), a kidney disease. Researchers compare it to an existing treatment, tacrolimus, to see how well it works in reducing protein in urine and improving kidney health.
United States · Argentina · Australia - recruitingPHASE2
Study of WAL0921 in Patients With Glomerular Kidney Diseases
This study is testing a new medicine, WAL0921, for people with certain kidney conditions, like diabetic kidney disease or rare kidney problems. It aims to see if the medicine is safe and effective in helping your kidneys. Some people will get the medicine, and others a dummy treatment.
United States · Australia · India - active not recruitingPHASE3
A Study Evaluating the Efficacy and Safety of Obinutuzumab in Participants With Primary Membranous Nephropathy
This study is looking at a new treatment called Obinutuzumab for a kidney condition called primary membranous nephropathy (pMN). It's a Phase 3 study, meaning it's well into testing, to see if this new medicine works better and is safer than current treatments.
United States · Argentina · Brazil - active not recruitingPHASE2, PHASE3
A Study to Examine the Efficacy and Safety of Zanubrutinib Given to Adults With Primary Membranous Nephropathy
This study is testing a new medicine called zanubrutinib for people with a kidney condition called primary membranous nephropathy. It compares zanubrutinib with a standard medicine, tacrolimus, to see how well it reduces protein in the urine and helps people get better.
United States · Brazil · Canada