- authorisedTherapeutic exploratory (Phase II)
A Phase 2a, Open-Label Pilot Study to Evaluate the Safety/Tolerability, Efficacy, Pharmacokinetics, and Pharmacodynamics of VTX2735 in Participants with Recurrent Pericarditis
This study is looking at a new medicine, VTX2735, for people who have recurring pericarditis (a heart condition). We want to check if it's safe, how well it works, and how the body handles it. This is an early-stage study.
Belgium - recruitingPHASE2
Transition to KPL-387 Monotherapy Dosing & Administration Study
This study looks at how people with recurrent pericarditis can safely switch from their usual medicines to a new drug called KPL-387. It checks if the new drug works well and if patients experience any side effects.
United States · Canada · France - ongoing, recruitingHuman Pharmacology (Phase I)- Other
Impact of CardiolRxTM on Recurrent Pericarditis: An open label Pilot Study
This study is looking into a new treatment called CardiolRxTM for people who have pericarditis that keeps coming back. It's a small, early-stage study to see if the treatment is safe and how it works.
France - recruitingPHASE2, PHASE3
Phase 2/3 Study of KPL-387 in Recurrent Pericarditis
This study is testing a new medicine, KPL-387, for people with recurrent pericarditis, a condition causing chest pain and inflammation around the heart. We want to see if it's safe and helps reduce symptoms and prevent the problem from coming back.
United States · Canada · France - authorisedTherapeutic confirmatory (Phase III)
IMpAct of CardiolRxTM oVer 6 months following IL-1 Blocker cessation in pERICarditis patients – MAVERIC: A randomized, double-blind, placebo-controlled trial
This study is testing a new medicine, CardiolRx, for people who have recurring episodes of pericarditis, which is swelling around the heart. It wants to see if CardiolRx can help prevent these episodes after stopping another treatment called an IL-1 blocker.
Greece · Italy