- authorisedHuman Pharmacology (Phase I)- Other
Study to assess the plasma concentration of rilzabrutinib given as a tablet to adult participants with severe renal impairment compared to matched participants with normal renal function
This study looks at how a medicine called rilzabrutinib behaves in the body. Researchers want to compare how people with severe kidney problems process this tablet compared to people with healthy kidneys. This helps doctors know if kidney disease changes the amount of medicine that stays in the blood.
Germany - recruitingHuman Pharmacology (Phase I)- Other
An Open-label, Single-dose Study to Evaluate the Effect of Renal Impairment on the Pharmacokinetics of JNJ-77242113 in Adult Participants
This study looks at how a new medicine, JNJ-77242113, moves through the body of adults with kidney problems. We want to see if kidney health changes how the medicine works, by giving one dose and checking blood levels.
Germany - recruitingHuman Pharmacology (Phase I)- Other
A Phase 1, Open-Label, Non-Randomized, Single-Center, Single-Dose Study to Assess the Pharmacokinetics and Safety of ANT3310 Combined with Meropenem Administered as a Single Intravenous Infusion to Adult Subjects with Renal Function Impairment
This study is looking at a new medicine called ANT3310, given with an existing antibiotic (Meropenem), to see how the body handles it and if it's safe for adults with kidney problems. It's an early-stage study, meaning it's one of the first times it's being tested in people.
Germany - recruitingHuman Pharmacology (Phase I)- Other
A study to test how kidney problems influence the blood concentrations of efgartigimod
This study looks at how a new medicine, called efgartigimod, is handled by the body in people with kidney problems. Researchers want to understand if kidney health affects the amount of the medicine in your blood.
Germany - recruitingHuman Pharmacology (Phase I)- Other
A Phase 1 Open-label, Parallel-Group, Single-Dose Study to Evaluate the Pharmacokinetics and Safety of Obeldesivir in Participants With Normal Renal Function and Renal Impairment
This study is looking at a new medicine called Obeldesivir for people with kidney problems. We want to see how the body handles the medicine and if it's safe. It's a very early study, focusing on how much medicine gets into the blood.
Germany - recruiting
Development of a Biomarker Panel for the Earlier Prediction of Acute Kidney Injury in Patients With Diabetes
This study looks for early warning signs of kidney problems in people with diabetes undergoing heart procedures. We want to find new ways to predict and prevent kidney damage caused by the dye used in these important tests, aiming to make them safer for more patients.
United Kingdom