- recruitingNA
HYPoxaEmic Respiratory Failure and Awake Prone Ventilation
This study looks at whether lying on your stomach (awake prone positioning) can help people with serious breathing problems avoid needing a breathing tube and machine. It's for adults with breathing difficulties not caused by COVID-19, using it alongside standard care.
Lithuania · United Kingdom - not yet recruiting
Investigating the Impact of Sepsis Phenotypes on Antibiotic Treatment in Patients With Severe Pneumonia and Sepsis
This study looks at how antibiotics work differently in people with severe pneumonia and sepsis. We want to understand if different immune system reactions affect antibiotic levels, aiming to improve treatment and fight antibiotic resistance.
United Kingdom - recruiting
Recovery From ICUAW Following Severe Respiratory and Cardiac Failure
This study looks at why some critically ill patients who need life support (ECMO) stay weak after leaving intensive care. We want to understand this weakness and how it affects their daily lives and well-being after severe heart and lung problems.
United Kingdom - recruiting
Comparison of Pulse Oximetry (SpO2) With Different Oximeters and Arterial Saturation (SaO2): Oxygap2 Study
This study compares different oxygen sensors (oximeters) used in hospitals. It checks how accurately they measure oxygen in your blood against a gold standard, aiming to improve how oxygen therapy is given to critically ill patients.
Canada - recruiting
Diaphragm Atrophy and Dysfunction in Mechanical Ventilation
This study looks at how mechanical breathing machines affect a muscle called the diaphragm. We want to understand how quickly the diaphragm can become weak and if it gets stronger again after the machine is stopped. This could help us better care for patients.
Germany - recruiting
OxyGap : Comparison Between Different Pulse Oximeter and With the Arterial Blood Gase
This study is checking how accurately different machines measure oxygen in the blood of intensive care patients. We want to make sure patients get the right amount of oxygen, as too much or too little can be harmful. The aim is to improve breathing support for people in critical care.
Canada - not yet recruitingNA
Safety, Tolerability and Performance of the NucleoCapture Device in the Reduction of Circulating CfDNA/NETs in Subjects with Sepsis
This study is testing a new device, NucleoCapture, for people with sepsis and breathing problems in intensive care. It aims to see if removing certain substances from the blood can improve treatment alongside standard care. Researchers are checking its safety and how well it works.
Germany · Switzerland · United Kingdom - recruiting
A Post Market Surveillance Study of the Hemovent Extracorporeal Cardiopulmonary Support System:The MOBYBOX Trial
This study looks at a special machine called MOBYBOX used to help people with serious heart or lung problems. It aims to check how safe and effective this machine is in real-world situations, helping doctors understand if it's working well.
Germany - recruiting
Benefit of Sleep Quality Monitoring by EEG in ICU
This study looks at how well a special brain monitor (EEG) can check sleep in critically ill patients with breathing problems. We want to see if it's better than nurses just watching. This could help improve how we look after patients in intensive care.
France - recruitingNA
Routine vs On-demand ECMO for Lung Transplantation
This study looks at the best way to use a heart-lung support machine (ECMO) during lung transplants. We're comparing using it for everyone versus only using it if a patient needs it during the operation for conditions like severe lung disease.
Canada - recruitingNA
High Flow Oxygen Therapy After Spinal Cord Injury
This study looks at a new way to give oxygen, called high-flow oxygen therapy, to people with spinal cord injuries in their upper back or neck. We want to see if it's practical to use and what effect it has on patients compared to standard care.
United Kingdom - recruiting
Diaphragm Structure and Pathobiology in Patients Being Bridged to Lung Transplant
This study looks at how breathing machines affect a muscle called the diaphragm in people waiting for a lung transplant. Researchers use ultrasound to see if different breathing supports cause different amounts of injury. The goal is to find the best ways to protect the diaphragm.
Canada - recruiting
Investigating Health Related Quality of Life in Patients With Chronic Respiratory Failure
This study looks at how chronic respiratory failure affects daily life for people in the UK. We want to understand their quality of life and how different treatments help.
United Kingdom