Rheumatoid arthritis (RA) research hub
11 indexed studies · 10 currently recruiting
- recruiting
A feasibility study of an online support programme to help South Asian people newly diagnosed with rheumatoid arthritis manage their condition
This study tests 'Apni Jung', a free online support programme for South Asian adults newly diagnosed with rheumatoid arthritis. Available in Hindi, Punjabi, and Urdu, it helps people understand and manage joint pain in daily life alongside their usual NHS care, testing if this approach works well for a larger future trial.
United Kingdom · England - recruiting
BloodTrackR Usability and Concordance Study (BUCS): Evaluating a Smart Home-Based Blood Collection Platform for Remote Monitoring in Rheumatoid Arthritis
This study looks at a new home blood testing kit, BloodTrackR, for people with rheumatoid arthritis. It checks how easy it is to use, if it reliably collects good blood samples, and if the results match hospital tests. The aim is to make monitoring easier from home.
United Kingdom - authorisedHuman Pharmacology (Phase I)- First administration to humans
A Study of LY4213663 in Healthy Participants and Participants With Rheumatoid Arthritis
This early-stage clinical trial is testing a new medicine called LY4213663. Researchers want to find out how safe it is and how it moves through the body. The study will test the medicine in both healthy volunteers and adults living with the joint condition rheumatoid arthritis.
Germany - recruitingTherapeutic exploratory (Phase II)
Randomized placebo-controlled trial comparing Methotrexate vs. Methotrexate/Metformin association in rheumatoid arthritis patients: METorMET² study.
This study looks at whether adding metformin, a common tablet for diabetes, to standard methotrexate treatment helps adults with rheumatoid arthritis. Doctors want to see if this combination reduces joint pain and swelling better than methotrexate alone, while also improving general health markers like weight and blood sugar.
France - recruitingTherapeutic exploratory (Phase II)
Phase IIa Proof-of-Concept Study, with Dose-Titration Based on Treat-to-Target Strategy, to Investigate the Efficacy, Safety, and Tolerability of Subcutaneous Injection of Folate-based Liposomes Encapsulating Methotrexate (FBL-MTX) in Disease-modifying Antirheumatic Drugs (DMARD)-naïve Patients with Moderate-to-Severe Active Rheumatoid Arthritis and in Patients with an Inadequate Response or Intolerance to Oral MTX.
This study tests a new injection for adults with moderate-to-severe rheumatoid arthritis. Researchers are testing a specially packaged form of methotrexate given under the skin. The aim is to see if it safely reduces joint swelling, pain, and stiffness, especially for people who struggled with standard tablets.
Portugal - recruitingPHASE1, PHASE2
Controlling Hyperactive Immunity With Long-lived Lymphocytes
This study tests a new treatment, QEL-005, for severe rheumatoid arthritis and systemic sclerosis. It aims to see if it's safe and helps improve symptoms. QEL-005 uses your own modified white blood cells to calm an overactive immune system.
Germany · Spain · United Kingdom - recruitingPHASE1
A Study of LY4213663 in Healthy Participants and Participants With Rheumatoid Arthritis
This study is testing a new medicine, LY4213663, for rheumatoid arthritis. We want to see if it's safe, what side effects it might cause, and how it works in the body. It includes healthy people and those with rheumatoid arthritis.
United States · Germany - not yet recruitingPHASE1
Study Investigating the Safety of Anti-CD19 CAR-T Cells Therapy Produced at Gustave Roussy for Adults With Severe and Refractory Systemic Autoimmune Rheumatic Diseases
This study is testing a new cell therapy called CAR-T for severe autoimmune diseases like rheumatoid arthritis and lupus. It's looking to see if the treatment is safe and helpful for adults when other treatments haven't worked, using a new method developed at Gustave Roussy.
France - not yet recruitingNA
Acceptability of a Nurse-led Telehealth Remote Self-monitoring Model of Care in Patients With Rheumatoid Arthritis
This study in Canada tests a new online system for people with Rheumatoid Arthritis (RA). Nurses help patients check their health from home, aiming to make care easier to access and improve how RA is managed, especially for those far from clinics.
Canada - recruiting
AYLo - AutoimmunitY and Loss of y
This study looks at how changes in your `Y` chromosome, which only men have, might be linked to certain long-term conditions like arthritis and similar diseases. Researchers want to understand if these changes affect how your immune system works and the progression of these conditions.
Germany - not yet recruitingNA
Personalized Outreach for Equitable Treatment in Rheumatology
This study looks at how we can help people with rheumatic diseases attend their clinic appointments in Vancouver. We're testing if offering a small payment or extra personal support can make a difference in helping people get the care they need.
Canada