- recruitingPHASE3
Cardiac Sarcoidosis Randomized Trial
This study compares two treatments for Cardiac Sarcoidosis: a standard dose of Prednisone (a steroid) versus a lower dose of Prednisone combined with Methotrexate. The aim is to find out if the combination treatment is just as effective but causes fewer side effects and improves quality of life.
United States · Canada · Japan - recruitingNA
Corticosteroid Tapering in Sarcoidosis
This study looks at how best to reduce prednisolone for sarcoidosis patients. It compares two ways of lowering the dose to find out which is safer and more effective, aiming to cut down side effects from long-term steroid use.
United Kingdom - recruiting
Mayo AVC Registry and Biobank
This study aims to better understand a heart condition called Arrhythmogenic Ventricular Cardiomyopathy (AVC) that can lead to sudden cardiac arrest. Researchers hope to find new genetic causes and ways to predict the disease, helping to save lives in affected families.
United States · United Kingdom - recruiting
AYLo - AutoimmunitY and Loss of y
This study looks at how changes in your `Y` chromosome, which only men have, might be linked to certain long-term conditions like arthritis and similar diseases. Researchers want to understand if these changes affect how your immune system works and the progression of these conditions.
Germany - active not recruitingPHASE3
Evaluation of TNF-alpha Antagonists (Infliximab) Withdrawal in Sarcoidosis
This study looks at whether stopping infliximab, a medicine for severe sarcoidosis, is safe. We want to see if staying on the medication for longer prevents the disease from coming back, compared to people who stop once their sarcoidosis is stable.
France - ongoing, recruitingTherapeutic use (Phase IV)
The PHENOSAR trial: Antibiotic treatment of biopsy confirmed phenotypes in sarcoidosis: a proof of concept clinical trial.
This study looks at how well two common antibiotics, Doxiclat and Azithran, might help reduce inflammation in people with sarcoidosis. It's an important step to see if these medicines could offer a new way to manage this condition.
Netherlands