- recruiting
Exploring the Lived Experience of Young Adults With Severe Asthma
This study explores the daily experiences of young adults (16-25) with severe or uncontrolled asthma in Manchester and Liverpool. We aim to understand their challenges and needs to improve future care and support for this group, which is often overlooked.
United Kingdom - recruitingNA
Deployment o the Multidisciplinary Prospective Cohort Imminent
This study aims to better understand long-term inflammatory diseases like lupus and severe asthma. Researchers will collect information and samples to find new ways to treat these conditions, reduce side effects, and improve daily life for patients. It's about finding better treatments for the future.
France - active not recruiting
Cohort Analysis of Clinical and Biological Severe Childhood Asthma
This study looks at children with severe asthma to understand why some children have it more seriously. Researchers will gather information and track their health over time. The goal is to find out what causes severe asthma and how it affects children as they grow up.
France - recruiting
Register Schweres Asthma - German Asthma Net e.V.
This study is gathering information about people in Germany who have severe asthma. It aims to understand the condition better, improve care, and learn more about how severe asthma affects people. They are collecting medical details over 15 years to help doctors find better ways to treat severe asthma.
Germany - authorisedTherapeutic use (Phase IV)
BIOlogical treatment GRAdual Interval Longing in severe Asthma (BIO-GRAIL)
This study looks at how new biological medicines help people with severe asthma. Researchers want to see if these treatments can keep asthma under control for about a year, even when the time between doses is made longer. It aims to improve asthma management and reduce flare-ups.
Netherlands - ongoing, recruitingTherapeutic exploratory (Phase II)
A Phase 2, Randomized, Double-blind, Placebo-controlled, Multi-center, Dose-ranging Study to Evaluate the Efficacy and Safety of Verekitug (UPB-101) in Adult Participants with Severe Asthma (VALIANT)
This study is testing a new medicine, Verekitug, for adults with severe asthma. We want to see if it can reduce severe asthma attacks and improve breathing over 60 weeks. Some people will get the medicine, others a dummy treatment, to see how well it works and if it's safe.
Czechia · Poland · Italy - recruitingPHASE3
A Study to Investigate GB-0895 Adjunctive Therapy in Adults and Adolescents With Severe Uncontrolled Asthma (SOLAIRIA-2)
This study is looking into a new treatment called GB-0895 for teenagers and adults with severe asthma that isn't well-controlled by usual medicines. Participants will receive either GB-0895 or a dummy treatment over about a year to see if it improves their health.
United States · Argentina · Australia - active not recruitingPHASE3
Open-label Study to Assess Reduction of Background Asthma Medication While Sustaining Asthma Control and Clinical Remission With Tezepelumab in Patients 12-80yrs With Severe Asthma.
This study looks at how well a new asthma medicine, tezepelumab, works to control severe asthma while patients try to reduce their regular asthma inhaler use. It aims to see if patients can stay well on less medicine.
United States · Argentina · Belgium - not yet recruiting
The Inflammatory Profile of Exacerbations in Patients With Severe Asthma Receiving Tezepelumab: The TezEx Study
This study looks into why some people with severe asthma still get flare-ups even when taking a new medicine called tezepelumab. Researchers want to understand the body's natural reactions better to help improve treatments for severe asthma.
United Kingdom - active not recruitingPHASE2
A Long-Term Safety and Efficacy Study of Verekitug (UPB-101) in Adult Participants With Severe Asthma (VALOUR)
This study looks at the long-term safety and effectiveness of a new medicine called verekitug (UPB-101) for adults with severe asthma. It's for people who have already finished a related study called VALIANT.
United States · Argentina · Bulgaria - recruiting
Experience of Biologic Treatments for Severe Asthma: a Survey
This survey aims to understand the real-life experiences of people with severe asthma using biologic treatments. We want to know how these treatments affect daily life, beyond just medical improvements, by asking about both positive changes and challenges like side effects.
United Kingdom - recruitingNA
Physical Activity Promotion and Clinical Remission in Severe Asthma
This study looks at whether adding a special exercise programme to standard severe asthma treatment (tezepelumab) helps more adults achieve remission. It aims to see if being more active can improve health outcomes for people with severe asthma.
United Kingdom