Severe hypertriglyceridemia (SHTG) research hub
3 indexed studies · 3 currently recruiting
- recruitingTherapeutic confirmatory (Phase III)
Double-Blind, Placebo-Controlled, Phase 3 Study to Evaluate the Efficacy and Safety of Plozasiran in Adults with Severe Hypertriglyceridemia (SHASTA-4 Study)
This Phase 3 clinical study tests a new injection called plozasiran for adults with very high blood fats, known as triglycerides. Researchers want to see if plozasiran can safely lower these fat levels over 12 months compared to a dummy jab, reducing the risk of painful pancreas inflammation.
Poland · Lithuania · Slovakia - recruitingTherapeutic confirmatory (Phase III)
Double-Blind, Placebo-Controlled, Phase 3 Study to Evaluate the Efficacy and Safety of Plozasiran in Adults with Severe Hypertriglyceridemia (SHASTA-3 Study)
This study tests a new injection called plozasiran for adults with very high blood fat levels, known as severe hypertriglyceridemia. Researchers want to see if the medicine can safely lower blood fats over one year compared to a dummy jab, reducing the risk of serious problems like pancreas inflammation.
Poland · Belgium · Czechia - recruitingPHASE1
A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory Dyslipidemias
This study is testing a new medicine called CTX310 for people in the UK with high cholesterol and fats in their blood that haven't improved with usual treatments. It will check if the medicine is safe and how well people tolerate different doses. It's an early-stage study.
United States · Australia · New Zealand