- enrolling by invitation
SMS - Study of Somatic Mutations Using Genome Sequencing
This study looks at how changes in our genes, called mutations, build up over our lives. Researchers want to understand if things like sunlight, smoking, or medical treatments affect these changes, and how they relate to ageing and health. They will study DNA from different types of samples.
United Kingdom - enrolling by invitation
Somatic Mutation in Chronic Liver Disease
This study looks at how liver cells change genetically during chronic liver disease, a problem that is becoming more common. Researchers hope to understand what causes these changes to help develop better ways to detect, treat, and predict outcomes for liver conditions and liver cancer.
United Kingdom - enrolling by invitation
Exploring the Landscape of Somatic Mutations in Human Tissue
This study looks at tiny changes in the body's cells, called mutations, in both healthy and unhealthy tissues. Scientists want to understand how these changes happen and why some parts of the body are more likely to develop them, which could help prevent diseases like cancer.
United Kingdom - enrolling by invitation
SMS 2: Impact of Cancer Therapy on the Somatic Mutational Landscape of Normal Tissues
This study looks at how cancer treatments, like chemotherapy or radiotherapy, affect tiny changes (mutations) in healthy body cells. We're collecting samples such as blood, cheek swabs, and urine from adult cancer patients to understand these changes better.
United Kingdom