- recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
RANDOMISED, CROSSOVER BIOEQUIVALENCE CLINICAL TRIAL OF APIXABAN 5 MG CAPSULES VS APIXABAN 5 MG FILM-COATED TABLETS, AFTER A SINGLE ORAL DOSE ADMINISTRATION TO HEALTHY VOLUNTEERS UNDER FASTING CONDITIONS
This study compares different forms of a blood-thinning medicine called apixaban (found in Eliquis) in healthy volunteers. We want to see if a new capsule version works the same way as the current tablet form when taken on an empty stomach. This helps ensure new medicines are safe and effective.
Spain - recruiting
The Origin and Role of Thromboembolism in the Pathogenesis of Ischaemic Stroke
This study looks at how blood clots cause strokes. We're using a special scan to find these clots and see where they come from. The aim is to better understand different types of stroke, especially when the cause isn't clear, to improve future treatments.
United Kingdom - active not recruiting
Are Uterine Fibroids Pro-thrombotic?
This study looks into whether having womb fibroids might increase your risk of blood clots. It compares blood samples from women with fibroids to those without, to see if fibroids alone make blood more prone to clotting. This could help improve how we assess and manage risk.
United Kingdom - active not recruiting
Searching for Explanations for Cryptogenic Stroke in the Young: Revealing the Etiology, Triggers, and Outcome
This study, SECRETO, looks into why younger adults have strokes when the cause isn't clear. It aims to find out what triggers these strokes, how people recover, and if genetics play a role, to help improve care for patients.
Estonia · Finland · Germany - recruitingPHASE3
Thromboprophylaxis in Lower Limb Immobilisation
This study looks at new ways to prevent blood clots after a leg injury treated with a cast or splint. It compares injections with tablets and also checks if medication helps those at lower risk of clots. The goal is to find safer and more effective options.
United Kingdom - recruiting
Adverse Drug Events in Patients on Oral Anticoagulation in the Emergency Department
This study looks at issues people on blood thinners face when they come to A&E. It aims to understand why these problems happen and how often, focusing on bleeding, clotting, and medication levels, to help improve care for patients.
France - recruitingPHASE4
Pre- Vs. Postoperative Thromboprophylaxis in Pancreatic Surgery
This study compares when to give blood clot prevention medicine for pancreatic surgery: either before or after the operation. It aims to find the safest and most effective timing to reduce risks like blood clots and bleeding. This is important because current guidelines differ.
Canada · Finland · Norway - recruiting
Non-invasive Coronary Thrombus Imaging to Define These Cause of Acute Myocardial Infarction
This study looks into a new scan that can detect blood clots in heart arteries after a heart attack. It aims to help doctors better understand what causes heart attacks and make sure patients get the right treatment.
United Kingdom