Topical pain research hub

A double-blind, prospective, randomised, placebo-controlled, single-centre, proof-of-principle trial in healthy volunteers to investigate safety, local tolerability, pharmacokinetics, and pharmacodynamics of Asacaine after topical administration on skin exposed to ultraviolet B radiation

This early-stage study tests a new pain-relief cream called Asacaine on healthy volunteers. Researchers use a mild dose of ultraviolet B (UVB) light to create temporary, sunburn-like skin tenderness. They then check how safe Asacaine is, how well the skin tolerates it, and if it eases mild skin pain.