Total Knee Arthroplasty research hub
12 indexed studies · 8 currently recruiting
- not yet recruitingNA
Gait in Fixed Or Rotating Cementless Total Knee Arthroplasties
This study compares two common knee replacement implants, Attune and Triathlon, which are designed to help people with painful knee arthritis. Researchers want to see if one implant helps patients walk better and feel more stable after surgery.
United Kingdom - recruiting
Multigen Plus CCK and AMF TT Cones Follow Up Study
This study looks at how well a specific knee replacement, called Multigen Plus CCK, works for people needing new or replacement knee surgery. It checks the knee’s condition and takes X-rays over two years.
Portugal · Slovakia · United Kingdom - authorisedTherapeutic confirmatory (Phase III)
Phase III Randomized, Double-Blind Clinical Trial to Determine the Role of Magnesium Sulfate in Adductor Canal Block in Total Knee Arthroplasty
This study looks at whether adding a special salt called magnesium sulfate to a pain-blocking injection (adductor canal block) helps people having knee replacement surgery. The aim is to see if it makes the pain relief last longer, meaning fewer strong painkillers are needed.
Spain - not yet recruiting
Biological Link Between Anxiety and Outcomes Post Knee Arthroplasty
This study looks at a possible link between feeling anxious or down before knee or hip replacement surgery and worse recovery. It explores if inflammation inside the joint is involved, using samples and questionnaires from people having these operations.
United Kingdom - active not recruiting
Comparing Temperature in Burr vs Saw Cutting for Knee Arthroplasty
This study compares how warm bones get during knee replacement surgery when using two different cutting tools: a burr (for robotic surgery) and a saw (for traditional surgery). We want to see if there's a difference in temperature.
United Kingdom - recruitingNA
Mako Cementless TKA vs Mako Cemented TKA
This study compares two ways to attach knee implants during total knee replacement surgery using a robotic arm. It looks at whether using 'cementless' or 'cemented' implants gives better results for people with knee arthritis, focusing on how well the knee works, X-ray findings, and overall patient experience.
United Kingdom - not yet recruitingNA
Local Infiltration Analgesia Versus Quadruple Nerve Blocks in Total Knee Arthroplasty.
This study compares two ways to manage pain after knee replacement surgery. One uses local pain relief directly in the knee, and the other uses special nerve blocks to numb the leg. The aim is to find the best way to help patients recover comfortably.
France - recruitingPHASE4
Kinematic and Mechanical Alignment Randomized Trial
This study compares two ways to do knee replacement surgery for arthritis: standard 'mechanical alignment' and a more personalised 'restricted kinematic alignment'. We want to see which method leads to better natural feel and movement using robotic help for precise surgery.
Canada - active not recruiting
Incidence of Adductor Canal Catheter Dislodgment
This study looks at how often a pain-relief tube, called an adductor canal catheter, moves out of place after knee replacement surgery. We want to find out why this happens and if it affects how well the pain relief works on the first day after the operation.
Canada - active not recruitingNA
A Study Using Metaphyseal Cones Versus a Cemented Stem Construct in Revision TKR
This study compares different ways to replace a knee that has already been replaced and failed. It looks at using extra cement or a special 'cone' to make the new knee stable. The goal is to find the best method for UK patients needing a second knee replacement.
United Kingdom - recruitingNA
Can the Use of Virtual Reality Improve TKA Outcomes
This study looks at whether using virtual reality (VR) during knee replacement surgery can help patients need less strong medicine to relax. It aims to see if VR can reduce side effects and help people recover faster after their operation.
United Kingdom - not yet recruitingNA
IMProving Outcomes With ACT After Knee Surgery
This study looks at a special type of therapy called Acceptance and Commitment Therapy (ACT) before knee replacement surgery. It aims to see if ACT can help people who are at higher risk of not doing as well after their surgery, especially if they feel down or worried.
United Kingdom