Uncomplicated acute appendicitis research hub
4 indexed studies · 0 currently recruiting
- authorisedTherapeutic use (Phase IV)
Optimizing the antibiotic treatment of uncomplicated acute appendicitis: a prospective randomized multicenter study
This study looks at different antibiotic treatments for mild appendicitis. Researchers want to see which antibiotics work best to avoid surgery and prevent the appendicitis from returning for at least a year. It's for adults aged 18 and over.
Finland - authorisedTherapeutic use (Phase IV)
Oral Antibiotic Outpatient Therapy vs. Placebo in the Treatment of Uncomplicated Acute Appendicitis: a Randomized Double-blind Placebo-controlled Noninferiority Trial APPAC IV
This study looks at whether antibiotics alone can treat mild appendicitis in adults, avoiding surgery. Half the patients get a common antibiotic, moxifloxacin, and the other half get a dummy pill (placebo). Doctors will check if the antibiotics successfully resolve the appendicitis without an operation.
Finland - authorisedTherapeutic use (Phase IV)
Antibiotic therapy vs. placebo in the treatment of acute uncomplicated appendicitis: a prospective randomized double-blind placebo-controlled trial - APPAC III
This study, called APPAC III, is looking at whether antibiotics can successfully treat acute appendicitis without surgery. We're comparing antibiotics to a dummy treatment to see if patients get better and avoid an operation. It's for adults with uncomplicated appendicitis.
Finland - authorisedPhase III and phase IV (Integrated)
“Study of pain syndrome and clinical-biochemical parameters in children aged 7 to 18 years in cases of non-surgical treatment of uncomplicated acute appendicitis”
This study looks at how a pain medicine, Ketorolac, works in children aged 7-18 with simple appendicitis that doesn't need surgery. Researchers are checking pain levels and body changes over 3 days.
Latvia