- enrolling by invitationPHASE3
A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension
This study looks at the long-term effects and safety of a drug called Ralinepag for people with a lung condition called pulmonary arterial hypertension (PAH). It's for those who have already tried Ralinepag in a previous study.
United States · Argentina · Australia - recruitingNA
Streamlined Denervation With spYral For an Optimized Treatment (SPYRAL SWYFT) in Subjects With Uncontrolled Hypertension
This study looks at a procedure called renal denervation to treat high blood pressure. It aims to see if a simpler way of doing the procedure is just as good, and possibly quicker, than older methods. This could offer a new option for people whose blood pressure is hard to control.
Australia · Belgium · Germany - active not recruitingNA
The RADIANCE II Pivotal Study: A Study of the ReCor Medical Paradise System in Stage II Hypertension
This study is testing a new device called the Paradise System for people with high blood pressure that's not too severe. It aims to see if this system, which treats kidney nerves, can safely and effectively lower blood pressure when people are taking few or no medications.
United States · Belgium · France - enrolling by invitation
Endtidal Carbon Dioxide for Earlier Detection of Pulmonary Hypertension
This study looks at a simple, affordable breath test to help diagnose a serious lung condition called pulmonary hypertension. Researchers want to see if measuring carbon dioxide in your breath can quickly show who might have this condition, potentially leading to earlier treatment.
Germany - active not recruitingPHASE2
A Study of Mosliciguat in PH-ILD
This study looks at a new inhaled medicine, mosliciguat, for people with high blood pressure in their lungs caused by lung scarring (PH-ILD). It checks if the medicine is safe and if it helps improve their condition. Participants will be given either the new medicine or a dummy medicine.
United States · Argentina · Australia - recruiting
Cardiovascular Longitudinal ALSPAC Research Investigations Following Hypertensive Pregnancy in Young Adulthood
This study looks at young adults (30-40 years old) who were born to mothers with high blood pressure during pregnancy. Researchers want to understand why these individuals might have higher risks of heart and blood vessel problems later in life and how to prevent them.
United Kingdom - recruiting
Hypertension Explored in Long-term Postpartum Follow-up in Later Life
This study looks at why women who had high blood pressure during pregnancy might get heart and blood vessel problems later in life. Researchers want to understand these changes better to find new ways to help them.
United Kingdom - recruitingNA
A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Understanding and Management of Coronary Calcium (The Optimal Trial)
This study compares two ways to plan heart artery procedures for people with hardened arteries. It uses advanced CT scans versus a standard internal ultrasound to see which method helps doctors work better and get similar good results for patients.
United States · Belgium · Spain - active not recruitingNA
SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN
This study looks at a treatment called renal denervation (RDN) for high blood pressure. It uses a device called Symplicity Spyral to see how well it works and if it's safe in the long term, especially for people whose blood pressure is hard to control.
United States · Australia · Belgium - recruitingNA
Smartphone Twelve-Lead ECG Utility In ST-Elevation Myocardial Infarction II
This study is testing a new smartphone device called AliveCor 12-lead ECG. It aims to see if this device can accurately detect heart attacks (STEMI and NSTEMI) in people with chest pain, just as well as the standard ECG machines used in hospitals.
United States · United Kingdom - active not recruitingNA
A Study of the ReCor Medical Paradise System in Clinical Hypertension
This study looks at a new ultrasound system, called Paradise®, to treat high blood pressure. It compares this new treatment with a pretend procedure to see how safe and effective it is for people with different types of high blood pressure.
United States · Belgium · France