Latest studies
- Recruiting
Sex differences in interoception and mental health: an investigation across the menstrual cycle
This study looks at how we sense internal body signals, like our heartbeat or breathing. Researchers want to discover whether these signals affect mental health differently in men and women, and how monthly hormonal cycles play a part. Participants aged 18 to 40 will track daily symptoms on an iPhone app for seven months.
Identifying sex differences in interoception (i.e. the perception of the internal state of the body), common mental health disorders (i.e. anxiety, depression) and mood, and somatic complaints (i.e. physical symptoms), and identifying whether the menstrual cycle may contribute to these differences.Luxembourg - Recruiting
Exploring the hidden burden of living with Glanzmann thrombasthenia
This study wants to hear from people living with Glanzmann thrombasthenia (GT) and their caregivers. We want to understand the daily challenges and feelings of those affected. Your stories can help improve support and understanding for everyone with GT.
Glanzmann thrombastheniaLuxembourg - RecruitingPhase I and Phase II (Integrated)- First administration to humans
A first-in-human proof-of-concept study with NVDX3, an osteogenic implant of human allogenic origin, in the treatment of distal radius fractures in adults.
This study is testing a new type of bone graft, called NVDX3, for broken wrists (distal radius fractures) in adults. It's a very early stage trial to see if it's safe and effective for people.
Distal radius fracturesLuxembourg - RecruitingPhase I and Phase II (Integrated)- First administration to humans
A proof-of-concept study with NVDX3, an osteogenic implant of human allogenic origin, in the treatment of low grade degenerative lumbar spondylolisthesis by interbody spine fusion in adults.
This study is looking at a new type of bone graft, called NVDX3, for adults with a common back problem called spondylolisthesis. It’s an early study to see if this new treatment is safe and works to help bones in the lower back fuse together.
Low grade degenerative lumbar spondylolisthesis by interbody spine fusionLuxembourg - RecruitingTherapeutic exploratory (Phase II)
Efficacy and Safety of AXL-Inhibitor bemcentinib for the Treatment of Moderate COVID-19 (AXL-SolidAct)
This study is testing a new medicine called bemcentinib for people with moderate COVID-19. It aims to see if the medicine can help them get better faster and prevent them from becoming more unwell. Researchers will also check if the medicine is safe to use.
SARS CoV-2 (COVID-19)Luxembourg - RecruitingTherapeutic confirmatory (Phase III)
European DisCoVeRy for Solidarity: An Adaptive Pandemic and Emerging Infection Platform Trial (SolidAct)
This study is looking at a new treatment called Baricitinib for people admitted to hospital with COVID-19. It aims to see if it can stop people from getting sicker or dying, compared to a dummy treatment.
SARS-CoV II infection (Coronavirus disease)Luxembourg - Enrolling by invitation
EuroSIDA - Clinical and Virological Outcome of European Patients Infected With HIV
The EuroSIDA study looks at how HIV affects people in Europe and how treatments work over time. It helps us understand health changes and the impact of new medicines for HIV and related conditions like hepatitis.
HIVHepatitis BHepatitis CAIDSLuxembourg - Not yet recruitingNA
Empowering Healthy Lifestyle Personalised Intervention to Prevent and Control Obesity: The HealthyW8 Project
The HealthyW8 study explores a digital tool to help different age groups, from children to older adults, make healthier lifestyle choices. It aims to prevent and manage obesity by offering personalised advice on diet, exercise, and sleep through apps and devices.
Obesity PreventionObesity and OverweightObesity and Obesity-related Medical ConditionsDigital HealthLuxembourg - Active not recruitingNA
Sedation, Temperature and Pressure After Cardiac Arrest and Resuscitation
This study looks at different ways to care for unconscious patients after a sudden heart stop. It tests varying levels of calming medicine, body temperature control, and blood pressure targets to see what helps patients recover best and survive longer.
Cardiac Arrest With Successful ResuscitationHypoxia, BrainLuxembourg - Active not recruiting
The MISTRAL Study: Gut Microbiome Correlates of Serious AIDS and Non-AIDS Events
The MISTRAL study investigates how gut bacteria affect people living with HIV, especially those over 50. It aims to find ways to improve health, reduce complications like inflammation, and make treatments and vaccines work better by understanding the gut microbiome.
HIV-1-infectionInflammationAIDSLuxembourg - Not yet recruitingPHASE2
Prevent Cognitive Decline in GBA-associated Parkinson's Disease
This study is testing a new medicine called prasinezumab to see if it can slow down memory and thinking problems in people with Parkinson's disease who have a specific genetic change. It involves monthly infusions over two years.
Parkinson's DiseaseLuxembourg - Active not recruitingPHASE2
A Study to Evaluate the Efficacy and Safety of Intravenous Prasinezumab in Participants With Early Parkinson's Disease
This study is looking into a new treatment called prasinezumab for people in the early stages of Parkinson's disease. Researchers want to see if it's safe and helps improve symptoms. Participants will either receive the new medicine or a dummy treatment, called a placebo.
Parkinsons DiseaseLuxembourg - Recruiting
Study to Learn More About the Safety and Effectiveness of the Drug VITRAKVI During Routine Use in Patients With TRK Fusion Cancer Which is Locally Advanced or Spread From the Place Where it Started to Other Places in the Body
This study looks at how well a drug called VITRAKVI works and how safe it is for people with TRK fusion cancer. This type of cancer happens when certain genes fuse together. Doctors want to see how VITRAKVI helps patients in real-world use.
Locally Advanced or Metastatic Solid Tumor Harboring an NTRK Gene FusionLuxembourg - Recruiting
PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort
This study aims to understand how Parkinson's disease progresses by tracking changes in people with Parkinson's, those at risk, and healthy volunteers. Scientists hope to find new ways to measure the disease's progression, which will help develop better treatments.
Parkinson DiseaseLuxembourg - Active not recruitingPHASE1, PHASE2
Open-Label Umbrella Study To Evaluate Safety And Efficacy Of Elacestrant In Various Combination In Participants With Metastatic Breast Cancer
This study is testing a new drug called elacestrant with other breast cancer medicines. It's for people with a specific type of advanced breast cancer that has spread. The main goals are to see if these drug combinations are safe and if they can help shrink the cancer.
Breast CancerMetastatic Breast CancerLuxembourg - Active not recruitingNA
Effects of Sedation, TEmperature and Pressure After Cardiac Arrest and REsuscitation on Major Adverse Kidney Events (STEPCARE-MAKE)
This study looks at how different ways of caring for people after a heart attack affect their kidneys. It checks if particular levels of sedation, temperature control, and blood pressure targets can help prevent kidney problems.
Acute Kidney FailureRenal Replacement Therapy for Acute Kidney Injury in ICUSedation in Intensive Care Unit PatientsSedation in the ICULuxembourg - RecruitingNA
AURORA: Aiming to Understand the Molecular Aberrations in Metastatic Breast Cancer.
The AURORA study aims to understand advanced breast cancer better. It collects tissue and blood samples from patients across Europe to find out why treatments work or don't. This research could help doctors find the best treatments for each patient in the future.
Metastatic Breast CancerLuxembourg - RecruitingNA
Stepcare Extended Follow-up Substudy
This study looks at how people recover for a long time after a serious cardiac arrest and how different treatments affect their memory and thinking. It also checks how caring for these survivors affects their family.
Cardiac Arrest With Successful ResuscitationHypoxia, BrainCognitive ImpairmentCaregiver BurdenLuxembourg