RecruitingOBSERVATIONAL

Acquisition and Long-term Observation of Patients With Severe Allergic Reactions

This study, called the Anaphylaxis Registry, is collecting important information from people who have experienced severe allergic reactions, known as anaphylaxis. The aim is to understand better what triggers these reactions, what symptoms people experience, and how they are currently managed. By gathering this data in a careful and organised way, researchers hope to improve how doctors diagnose anaphylaxis and how patients are cared for over the long term. This could lead to a better understanding of why these reactions happen and how to prevent them. Taking part is about sharing your experience, and it could help doctors develop better treatments and advice for everyone affected by severe allergies.

At a glance

Status

Recruiting

Sponsor

Charite University, Berlin, Germany

Enrolment target

20,000

Start

01 Jan 2007

Estimated completion

01 Dec 2030

Anaphylaxis

What is this study about?

Imagine a jigsaw puzzle where each piece is a bit of information about severe allergic reactions. This study, called the Anaphylaxis Registry, is trying to put all those pieces together. Researchers want to collect information in a consistent way from people who have experienced anaphylaxis – that's a very serious, whole-body allergic reaction.

The main goal is to get a clearer picture of what causes these reactions, like specific foods, insect stings, or medicines. They also want to understand the different symptoms people have, and what treatments work best. By collecting lots of details about many different people, the researchers believe they can find patterns. This knowledge could lead to better ways for doctors to diagnose anaphylaxis and help people manage their condition over many years.

Ultimately, the study aims to improve the lives of people with severe allergies. By understanding more about what happens in the body during anaphylaxis and what can trigger it, doctors might be able to offer more accurate advice, potentially leading to fewer reactions and better peace of mind for those affected. It's all about learning from shared experiences to make future care better.

Key takeaways

This study collects information about severe allergic reactions (anaphylaxis).
It aims to understand triggers, symptoms, and treatment approaches.
Your participation helps improve future diagnosis and care for others.
It's an observational study – no new medicines are given.
Providing a blood sample is optional but helpful.
You can stop participating at any time.

Who may be eligible?

This study is looking for people of all ages and genders to take part. It's open to anyone who has experienced a severe allergic reaction, also known as anaphylaxis, within the last 12 months. This means if you've recently had such a reaction, you might be able to join.

There are no specific reasons given why someone would be unable to join the study, other than the main requirement of having had a severe allergic reaction recently. If you're unsure whether your reaction counts as anaphylaxis, your doctor can help you with that.

If you meet this main requirement and are interested in contributing, you're encouraged to speak with your doctor to learn more.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

I have had a severe allergic reaction (anaphylaxis) in the last 12 months.
I am willing to share information about my reaction and its management.
My age is not a barrier (all ages can participate).
My gender is not a barrier (all genders can participate).

Answer every question to see your result.

What does participation involve?

This is an observational study, which means you won't be given any new medicines or treatments as part of the study. You'll continue with your usual medical care. Taking part primarily involves sharing information about your severe allergic reactions. This includes details about your symptoms, what you think caused your reaction, and how it was treated.

There's an optional part where you can choose to provide a blood sample. This sample would help researchers understand your allergy profile better. They believe there might be special markers in the blood that are linked to anaphylaxis, and this could help predict or understand reactions better in the future. The total duration of your participation will involve sharing information about your experiences as requested by the study.

Potential risks and benefits

The potential benefits of taking part in this study are not directly for you as an individual, but for others. By sharing your experience, you'll be contributing to a greater understanding of severe allergic reactions, which could lead to better diagnosis, prevention, and long-term care for people with anaphylaxis in the future. The risks of participating are generally low as there are no experimental treatments involved. If you choose to give a blood sample, there's a small risk of discomfort or bruising, similar to any blood test. You have the right to withdraw from the study at any time, for any reason, without it affecting your usual medical care.

Locations (1)

Charité - Universitätsmedizin Berlin
Verified postcode
Berlin, Germany· Recruiting

Common questions

What is anaphylaxis?

Anaphylaxis is a very serious, sudden, and potentially life-threatening allergic reaction that affects your whole body.

Will I get new medicine or treatment?

No, this study is about collecting information, not giving new treatments. You will continue with your usual medical care.

Do I have to give a blood sample?

No, giving a blood sample is completely optional. You can still take part in the study without providing one.

How long will I be involved in the study?

The study aims to observe and collect information over time. The exact duration will depend on what information is gathered.

What will happen to my information?

Your information will be used to help researchers learn more about severe allergic reactions, trying to find patterns and improve care for everyone.

How to find out more

Margitta Worm, Prof.

margitta.worm@charite.de +49 30 450 518105 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.