European All-comers' Multicentric Prospective REGISTRY on LUMINOR© Drug Eluting Balloon in the Superficial Femoral Artery and Popliteal Artery With 5 Years Follow-up.

To be considered for this study, you need to be at least 18 years old and have problems with blood flow in your legs (Peripheral Arterial Disease), causing symptoms ranging from pain when walking to more severe issues like ulcers. The blockages in your upper leg arteries must be quite significant (at least 70% blocked) or completely closed off.

Doctors will need to be able to successfully guide a wire past the blockage and perform an initial balloon widening of the artery. It's also important that you have at least one clear blood vessel flowing down to your ankle. You also need to be willing to commit to 5 years of follow-up appointments.

However, you cannot join if you are pregnant, breastfeeding, planning to become pregnant, or if you are a man planning to father children. You also can't participate if your doctors believe you have less than a year to live, or if you are already in another medical study involving a new drug or device, or if the LUMINOR© balloon is not suitable for you according to its instructions.

If you join this study, you will have a procedure to open your blocked leg artery using the LUMINOR© drug-eluting balloon. After the procedure, you will have regular check-ups and assessments over a period of 5 years. These follow-up appointments are crucial to track how well the artery stays open and how your symptoms progress over time. The exact number and type of visits will be explained by the study team, but they will likely involve consultations and imaging tests to monitor your blood vessels.